{"id":"W4399483715","doi":"10.1136/annrheumdis-2024-eular.4851","title":"AB0092 COVID-19 MRNA VACCINES BASED ON THE ANCESTRAL WUHAN STRAIN GENERATE ANTI-SARSCOV2 ANTIBODIES WITH LOW VIRAL INHIBITION LEVELS TO OMICRON VARIANTS IN PEOPLE WITH IMMUNE MEDIATED INFLAMMATORY DISEASES","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Public Health Agency of Canada; University of Manitoba","funders":"","keywords":"Virology; Antibody; Strain (injury); Coronavirus disease 2019 (COVID-19); Immune system; Messenger RNA; Biology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Immunology; Medicine; Gene; Genetics; Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039177,0.0003422902,0.0002681674,0.0002075527,0.0001907693,0.000242571,0.0001631772,0.000380076,0.002672106],"category_scores_gemma":[0.0001938291,0.0001123571,0.000217667,0.0001035427,0.0002145395,0.0001814569,0.0002102476,0.0008339643,0.0005264824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002737992,"about_ca_system_score_gemma":0.0002319831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363546,"about_ca_topic_score_gemma":0.001490703,"domain_scores_codex":[0.9998255,0.00002643272,0.000009997532,0.00003352236,0.00004950335,0.00005505354],"domain_scores_gemma":[0.9999427,0.000008695264,0.00001039159,0.000009657613,0.00001383532,0.00001482986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002634673,0.0002445033,0.001732274,0.00002499813,0.00001955819,0.00006603576,0.00003115628,0.00009859091,0.9880846,0.0002331566,0.0003209396,0.008880662],"study_design_scores_gemma":[0.0003107636,0.006656022,0.02976137,0.00002902579,0.0001193093,0.001054929,0.0001612888,0.002199514,0.9443831,0.0002985246,0.0150076,0.0000184607],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995508,0.000309101,0.00138906,0.0001289143,0.00007603312,0.00006334885,0.0001922227,0.00007819122,0.00225502],"genre_scores_gemma":[0.9948672,0.0001598672,0.001173355,0.0001347945,0.00002231814,0.00004501175,0.0003669055,0.00002292092,0.003207715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002672106,"threshold_uncertainty_score":0.008939087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067668725872514,"score_gpt":0.2728444136770512,"score_spread":0.2521677264183261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}