{"id":"W4399484434","doi":"10.1136/annrheumdis-2024-eular.774","title":"OP0247 EFFICACY OF A NOVEL LONG-ACTING FLUTICASONE PROPIONATE INTRA ARTICULAR INJECTION (EP-104IAR) IN KNEE OSTEOARTHRITIS: PER-PROTOCOL ANALYSIS OF A RANDOMISED, DOUBLE-BLIND, PHASE 2 TRIAL OF EP-104IAR VS VEHICLE PLACEBO (SPRINGBOARD)","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Intramuscular injections and effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Osteoarthritis; Medicine; Double blind; Intra articular; Fluticasone propionate; Viscosupplementation; Internal medicine; Corticosteroid; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001161335,0.0002800962,0.001278553,0.0008158812,0.00007298525,0.00003635903,0.0001864833,0.0001286941,0.0001326201],"category_scores_gemma":[0.001397531,0.0002047084,0.001167186,0.00178242,0.0002716198,0.0001717916,0.0000914757,0.000246839,0.000002873048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004584301,"about_ca_system_score_gemma":0.0003127777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003095552,"about_ca_topic_score_gemma":0.00003212502,"domain_scores_codex":[0.9968366,0.0002726648,0.001472364,0.0003621655,0.0007228195,0.0003334061],"domain_scores_gemma":[0.9975602,0.0007067829,0.0005906951,0.0006505885,0.0003490185,0.0001427397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8733057,0.01266094,0.0008557681,0.01038195,0.007962843,0.00003824173,0.002436829,0.01357673,0.01595169,0.0004602724,0.0001069305,0.06226214],"study_design_scores_gemma":[0.7946417,0.006032685,0.004003759,0.01250195,0.008996181,0.00003566697,0.0008277379,0.1043996,0.06792398,0.0001001188,0.00006593214,0.0004706082],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680728,0.0004265865,0.001038335,0.0002279142,0.000190156,0.02987094,0.00005252469,0.00003978349,0.00008100595],"genre_scores_gemma":[0.9926062,0.00002987997,0.0001768994,0.00002343593,0.0000518077,0.007012437,0.00002320769,0.00003483799,0.00004129161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0908229,"threshold_uncertainty_score":0.8347768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04582983256129165,"score_gpt":0.3703576504167505,"score_spread":0.3245278178554588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}