{"id":"W4399484434","doi":"10.1136/annrheumdis-2024-eular.774","title":"OP0247 EFFICACY OF A NOVEL LONG-ACTING FLUTICASONE PROPIONATE INTRA ARTICULAR INJECTION (EP-104IAR) IN KNEE OSTEOARTHRITIS: PER-PROTOCOL ANALYSIS OF A RANDOMISED, DOUBLE-BLIND, PHASE 2 TRIAL OF EP-104IAR VS VEHICLE PLACEBO (SPRINGBOARD)","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Intramuscular injections and effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Osteoarthritis; Medicine; Double blind; Intra articular; Fluticasone propionate; Viscosupplementation; Internal medicine; Corticosteroid; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00366158,0.002498789,0.004415485,0.0009779577,0.0004047687,0.001250315,0.001480855,0.002682099,0.01236877],"category_scores_gemma":[0.002559441,0.001152957,0.00351271,0.0006772162,0.001700311,0.001883292,0.0005853539,0.003595799,0.001670297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006407413,"about_ca_system_score_gemma":0.001268677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008157884,"about_ca_topic_score_gemma":0.00151025,"domain_scores_codex":[0.9985046,0.0008342463,0.0001147664,0.0002135376,0.000108223,0.000224614],"domain_scores_gemma":[0.9987782,0.0004904583,0.0002622771,0.000128044,0.00007111675,0.0002699685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.980985,0.004426383,0.0001118017,0.0005678277,0.0005998722,0.00002241227,0.00002864376,0.000198771,0.003139812,0.00006387055,0.0002472842,0.009608276],"study_design_scores_gemma":[0.9178514,0.08038404,0.0006956761,0.000022027,0.0002909135,0.00001510251,0.0000118137,0.000190084,0.0003290204,0.000048499,0.0001482168,0.00001319808],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804438,0.005272643,0.002043327,0.00048534,0.0006811601,0.006716987,0.001690548,0.0003988791,0.002267154],"genre_scores_gemma":[0.9745051,0.003343573,0.004067407,0.0008442477,0.0006572268,0.01007663,0.001652748,0.00008704486,0.004766112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01236877,"threshold_uncertainty_score":0.04137766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04582983256129165,"score_gpt":0.3703576504167505,"score_spread":0.3245278178554588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}