{"id":"W4399495182","doi":"10.3390/cells13121010","title":"Efficient Generation of Pancreatic Progenitor Cells from Induced Pluripotent Stem Cells Derived from a Non-Invasive and Accessible Tissue Source—The Plucked Hair Follicle","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Mitacs","keywords":"Induced pluripotent stem cell; Reprogramming; Regenerative medicine; Progenitor cell; Stem cell; Hair follicle; Biology; Cell biology; PDX1; Stromal cell; Cancer research; Immunology; Embryonic stem cell; Cell; Endocrinology; Insulin; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002345838,0.0002136703,0.0001976373,0.000280211,0.0001625912,0.0004275065,0.0002546937,0.000248428,0.0008768397],"category_scores_gemma":[0.0001635801,0.000112167,0.0002504679,0.000219996,0.0001501307,0.0002569256,0.0003407561,0.0006480715,0.0004325098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001094622,"about_ca_system_score_gemma":0.0002382437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001961344,"about_ca_topic_score_gemma":0.0002792038,"domain_scores_codex":[0.9998603,0.00001068514,0.00002162396,0.00002860909,0.00006090424,0.00001789835],"domain_scores_gemma":[0.999929,0.000009171788,0.00001811614,0.00001591328,0.00001588752,0.00001197956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003913941,0.00003084891,0.0005813888,0.00008622533,0.000007241555,0.0001975005,0.00005703892,0.0002620038,0.9891329,0.0003676301,0.0001117473,0.009126294],"study_design_scores_gemma":[0.00001253856,0.0002119637,0.002448162,0.00003104571,0.00002963614,0.0007115507,0.00007665309,0.001961766,0.9851508,0.0002186473,0.009138295,0.000008982392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8774964,0.003132622,0.1084355,0.0002289936,0.0001198094,0.0005943634,0.002278796,0.0004720848,0.007241465],"genre_scores_gemma":[0.9396555,0.003444233,0.04944869,0.0001317445,0.00002513337,0.0002977477,0.002607152,0.00008125372,0.004308703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008768397,"threshold_uncertainty_score":0.002933323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02179262910363435,"score_gpt":0.2570710976250599,"score_spread":0.2352784685214256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}