{"id":"W4399539054","doi":"10.2196/preprints.62659","title":"Effectiveness of Stromal Vascular Fraction (SVF) and Platelets Rich Plasma (PRP) in patients with Osteoarthritis: Study protocol for a phase III, prospective, randomized, controlled multi-center study: (SPOST study). (Preprint)","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; Platelet-rich plasma; Stromal vascular fraction; WOMAC; Clinical endpoint; Clinical trial; Physical therapy; Randomized controlled trial; Surgery; Internal medicine; Stromal cell; Pathology; Platelet; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01023275,0.002863943,0.00465494,0.000924886,0.001192124,0.001569843,0.001769983,0.003432483,0.02835953],"category_scores_gemma":[0.007476744,0.001347996,0.002755598,0.00123686,0.001806979,0.001481696,0.0007813397,0.004046355,0.006434809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001379366,"about_ca_system_score_gemma":0.00641323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007833909,"about_ca_topic_score_gemma":0.001751435,"domain_scores_codex":[0.9959404,0.002423525,0.0004331261,0.0003764569,0.0004078692,0.0004186432],"domain_scores_gemma":[0.9962294,0.0007568807,0.0009913996,0.0005102865,0.0005723824,0.0009395735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9642897,0.01309961,0.0004974934,0.002543585,0.0005031829,0.00005076266,0.00006752517,0.0004822914,0.002898593,0.0003798718,0.004519534,0.0106678],"study_design_scores_gemma":[0.9327409,0.05969267,0.001247295,0.0002053464,0.0002432767,0.00002481102,0.00001941978,0.0002299766,0.0005108964,0.000233481,0.004826411,0.00002539904],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.05214854,0.001689363,0.002816385,0.0006671362,0.0006728221,0.934429,0.004752742,0.0002686225,0.002555343],"genre_scores_gemma":[0.04021043,0.0008671167,0.004973528,0.001002069,0.0003097236,0.9488879,0.001803139,0.00003053045,0.001915561],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02835953,"threshold_uncertainty_score":0.09487206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217792600258133,"score_gpt":0.3278650981405815,"score_spread":0.3156871721380001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}