{"id":"W4399544630","doi":"10.20944/preprints202406.0633.v1","title":"The Iron Chelator, DIBI, Reduces Bacterial Load and Inflammation in Experimental Lung Infection","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Bronchoalveolar lavage; Lung; Inflammation; Immune system; Pharmacology; Medicine; Pseudomonas aeruginosa; Immunology; Chemistry; Bacteria; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002973313,0.0004483361,0.0006204477,0.0004962306,0.0002273688,0.0002733135,0.0002906132,0.0005591705,0.001283038],"category_scores_gemma":[0.0002709473,0.0001764661,0.0002346595,0.0001988509,0.0003898654,0.0003103559,0.0002696058,0.0008740241,0.0003198439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002236393,"about_ca_system_score_gemma":0.0003443834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005698326,"about_ca_topic_score_gemma":0.0007745879,"domain_scores_codex":[0.9998409,0.00003388065,0.00001201119,0.00002561253,0.00004517987,0.00004239207],"domain_scores_gemma":[0.9998624,0.00002247491,0.00003523389,0.00001586,0.00001958484,0.0000444184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001278214,0.0003789614,0.0001700354,0.0001466114,0.00001156305,0.00004939464,0.00004103384,0.00009163754,0.9935728,0.00006750828,0.0001440896,0.004047995],"study_design_scores_gemma":[0.00008317664,0.002887218,0.002400252,0.0000239759,0.00003691297,0.0001492676,0.00003549967,0.0006073156,0.9912559,0.0000771477,0.002436032,0.000007355586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827592,0.008156287,0.005523894,0.0006764183,0.0002481106,0.0001011014,0.0003056669,0.0002583395,0.001970883],"genre_scores_gemma":[0.9796357,0.004725688,0.007445457,0.0002536403,0.00008815219,0.0001612536,0.0006222627,0.00007391377,0.006993796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001283038,"threshold_uncertainty_score":0.00429225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05251001764590299,"score_gpt":0.347664731036083,"score_spread":0.29515471339018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}