{"id":"W4399560389","doi":"10.1021/acs.est.4c04633","title":"Detection of Chronic Wasting Disease Prions in Prairie Soils from Endemic Regions","year":2024,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Government of Saskatchewan; Ministry of Environment; University of Saskatchewan; University of Alberta","funders":"Genome Alberta; Genome Canada; Alberta Innovates Bio Solutions; North Dakota Game and Fish Department; Results Driven Agriculture Research","keywords":"Chronic wasting disease; Soil water; Feces; Transmission (telecommunications); Horizontal transmission; Veterinary medicine; Biology; Prion protein; Ecology; Disease; Virology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004009463,0.0003427207,0.0002196101,0.001052915,0.0004800077,0.0007191978,0.0002849422,0.0002521127,0.0002842246],"category_scores_gemma":[0.0005150059,0.0002234764,0.0001110042,0.0008163269,0.0004094061,0.0002196627,0.0003423204,0.0002333762,0.0001316904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002919573,"about_ca_system_score_gemma":0.0004667148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01712124,"about_ca_topic_score_gemma":0.044316,"domain_scores_codex":[0.9996824,0.00005100679,0.00003873176,0.0001018964,0.0000822899,0.0000435511],"domain_scores_gemma":[0.9994206,0.00008542163,0.0001872057,0.00002586278,0.0002060884,0.0000748163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001217625,0.00006887885,0.4980443,0.0001200738,0.00005660959,0.0002971408,0.0009352001,0.00008492653,0.4953082,0.00004077,0.00004683898,0.00487527],"study_design_scores_gemma":[0.000008062505,0.0002396686,0.9734264,0.00002275116,0.00004013162,0.0006187346,0.001239926,0.000280236,0.02360221,0.00003965637,0.0004714001,0.00001083946],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989925,0.0001618215,0.0003649667,0.000008942787,0.000001881932,0.00001531084,0.0001773229,0.000004263255,0.0002729241],"genre_scores_gemma":[0.9965932,0.0004543683,0.002071241,0.00002942846,0.000003322537,0.00002052373,0.0005029509,0.000002845361,0.0003220955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01712124,"threshold_uncertainty_score":0.03404313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005517642069055004,"score_gpt":0.2296485459521109,"score_spread":0.2241309038830559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}