{"id":"W4399563075","doi":"10.1109/lsens.2024.3413575","title":"Comparison of Aptamer and Antibody Bioreceptors in the OEGFET Biosensor Platform for Detecting α-Synuclein, a Parkinson's Biomarker","year":2024,"lang":"en","type":"article","venue":"IEEE Sensors Letters","topic":"Conducting polymers and applications","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Biomarker; Biosensor; Antibody; Nanotechnology; Chemistry; Molecular biology; Computational biology; Virology; Biology; Materials science; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007339701,0.000562019,0.0002941682,0.0002881506,0.0001129842,0.0004431074,0.000706649,0.001180982,0.0003348182],"category_scores_gemma":[0.0008846945,0.0002204863,0.0003340951,0.0001652645,0.0002159776,0.0005964991,0.0002855653,0.0004022006,0.0002478304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003113832,"about_ca_system_score_gemma":0.0001883095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006754887,"about_ca_topic_score_gemma":0.0009024622,"domain_scores_codex":[0.9994135,0.0001219512,0.00004525286,0.0001115386,0.000220337,0.00008742614],"domain_scores_gemma":[0.999767,0.00006879421,0.00003577147,0.00001190622,0.00008725828,0.00002924657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005880172,0.00001542855,0.00006558897,0.00004207963,0.000004330937,0.00003352892,0.00001709435,0.0001319393,0.9981061,0.0000803846,0.00002401053,0.001420716],"study_design_scores_gemma":[0.00001333233,0.000615393,0.0009016478,0.0000100674,0.00002162551,0.0002403024,0.00003433935,0.003793126,0.9929148,0.00005582115,0.001387162,0.00001230673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.966382,0.005048249,0.02599572,0.0002492135,0.0001607669,0.0001216941,0.0001145475,0.0001667152,0.001761057],"genre_scores_gemma":[0.9576111,0.002407437,0.03689068,0.0004050078,0.00003036041,0.0001307305,0.0002011012,0.00002073837,0.002302792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001180982,"threshold_uncertainty_score":0.003881633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05175845293884391,"score_gpt":0.3427394948232335,"score_spread":0.2909810418843896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}