{"id":"W4399597185","doi":"10.1093/ismejo/wrae102","title":"Leveraging genome-scale metabolic models to understand aerobic methanotrophs","year":2024,"lang":"en","type":"review","venue":"The ISME Journal","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Grantová Agentura České Republiky","keywords":"Biology; Ecology; Microbial ecology; Methanogenesis; Biochemical engineering; Methane; Bacteria; Genetics; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007511951,0.0004657651,0.0009072426,0.000194412,0.0002501769,0.0001869236,0.000606553,0.0002848779,0.00006941398],"category_scores_gemma":[0.00001645447,0.0002786378,0.0007368573,0.0003090324,0.00004675829,0.000008645006,0.0002913268,0.0007447713,0.0001890797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005843581,"about_ca_system_score_gemma":0.0003235957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001087424,"about_ca_topic_score_gemma":0.00000739124,"domain_scores_codex":[0.9980301,0.0003000653,0.0005593135,0.0004363282,0.0002297146,0.000444436],"domain_scores_gemma":[0.998969,0.00001270245,0.0002224663,0.0005271864,0.00007243305,0.0001962431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001016379,0.0001047875,7.13375e-8,0.003948085,0.003646125,0.00004828674,0.002196701,0.00314115,0.03398458,0.0006043852,0.1662307,0.7859935],"study_design_scores_gemma":[0.0001117855,0.00005091352,1.832664e-7,0.0006869866,0.002009355,0.0007522349,0.0001107464,0.000007478054,0.0001904768,0.0004703294,0.9952757,0.0003337652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002230982,0.9789078,0.01811449,0.0001591512,0.001830549,0.0003518199,0.00005449575,0.00001617855,0.0003423837],"genre_scores_gemma":[0.0001043749,0.9914209,0.0006367994,0.0003590822,0.003295954,0.00001389798,0.00005474572,0.0001098066,0.004004415],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.829045,"threshold_uncertainty_score":0.9999666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07212476257052353,"score_gpt":0.3038069619577346,"score_spread":0.2316821993872111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}