{"id":"W4399603814","doi":"10.1016/j.stemcr.2024.05.005","title":"A dual-color PAX7 and MYF5 in vivo reporter to investigate muscle stem cell heterogeneity in regeneration and aging","year":2024,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de recherche du Québec – Nature et technologies; Deutsche Forschungsgemeinschaft; Stem Cell Network","keywords":"MYF5; Biology; Stem cell; Cell biology; Regeneration (biology); Myocyte; Myogenesis; MyoD","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004551872,0.0004190732,0.0002959515,0.0007888869,0.0002462592,0.0003150162,0.0004986397,0.0005510623,0.001703671],"category_scores_gemma":[0.0001128004,0.0002957921,0.000307124,0.0002387679,0.0004068573,0.0003838183,0.0004462554,0.000767789,0.0004285621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003152652,"about_ca_system_score_gemma":0.0002150015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005413513,"about_ca_topic_score_gemma":0.001073437,"domain_scores_codex":[0.9997414,0.00003808533,0.00002078962,0.00008281659,0.00007346245,0.00004360703],"domain_scores_gemma":[0.9998467,0.00002467775,0.00004975856,0.00001863574,0.00001597554,0.0000443433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000277507,0.00001173571,0.0001497981,0.00001136923,0.000002325207,0.00001593496,0.00001466787,0.00002620827,0.9986783,0.0002561199,0.00001814073,0.0007876035],"study_design_scores_gemma":[0.000007991732,0.0001631437,0.001821573,0.000005245396,0.00001327654,0.0002806437,0.00002595767,0.001314174,0.9941724,0.00009755886,0.0020931,0.000004989955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9083117,0.002141687,0.08465513,0.0002112875,0.00007587895,0.000130938,0.0008214323,0.0004310588,0.003220918],"genre_scores_gemma":[0.9332959,0.001350284,0.05292649,0.0001304365,0.00002296814,0.0002004862,0.001170051,0.0001693475,0.01073418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001703671,"threshold_uncertainty_score":0.005699396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009874187465702582,"score_gpt":0.2331259723935415,"score_spread":0.2232517849278389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}