{"id":"W4399604997","doi":"10.1038/s41591-024-03130-3","title":"Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo","year":2024,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":356,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; McMaster University; Impact","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Fogarty International Center; Defense Threat Reduction Agency; Vlaamse regering; Fonds Wetenschappelijk Onderzoek; Wellcome Trust; Institut de Recherche pour le Développement; University of Pittsburgh; U.S. Department of Defense; World Health Organization; U.S. Department of Agriculture; Universiteit Stellenbosch; Case Western Reserve University; National Institutes of Health; U.S. Department of Health and Human Services; International Development Research Centre","keywords":"Clade; Monkeypox; Outbreak; Transmission (telecommunications); Lineage (genetic); Subclade; Virology; Biology; Phylogenetics; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001862998,0.0001503003,0.00009890494,0.0003256152,0.0005467414,0.0005367518,0.0001191134,0.0002121498,0.0004167284],"category_scores_gemma":[0.0005125178,0.00008887763,0.0000811694,0.0003097703,0.0002796438,0.000213546,0.0002393267,0.0002422721,0.00005694113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006123789,"about_ca_system_score_gemma":0.0002007443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01118652,"about_ca_topic_score_gemma":0.01204108,"domain_scores_codex":[0.9998854,0.00003710529,0.00001109284,0.00002454829,0.00001331749,0.00002840388],"domain_scores_gemma":[0.9997888,0.00003683654,0.00009987471,0.00001287476,0.00001798392,0.00004360436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002775894,0.00004358745,0.9709761,0.00004273384,0.0000372166,0.003250602,0.001493708,0.0003549034,0.01390868,0.0001505292,0.0004340647,0.009030226],"study_design_scores_gemma":[0.00001295071,0.000121004,0.989499,0.00003333094,0.00002069565,0.004443037,0.001786317,0.0004635558,0.001686131,0.00006186565,0.001862415,0.000009597682],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993438,0.0001137903,0.00005633914,0.00006239447,0.000001420056,0.000006330367,0.0001222212,0.000002173874,0.0002915655],"genre_scores_gemma":[0.999568,0.00009044192,0.0001147071,0.00003136889,0.000003674696,0.000003880228,0.0001142079,6.693874e-7,0.00007307347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01118652,"threshold_uncertainty_score":0.02224278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01605811301948845,"score_gpt":0.3173617150882975,"score_spread":0.301303602068809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}