{"id":"W4399622841","doi":"10.7554/elife.93077.2.sa1","title":"Reviewer #1 (Public Review): A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children","keywords":"In vivo; Zebrafish; Glioblastoma; Inhibitory postsynaptic potential; Inflammation; Cancer research; Medicine; Biology; Immunology; Neuroscience; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02319928,0.001410093,0.003016319,0.002760417,0.00203895,0.006749621,0.005115442,0.01673723,0.0631386],"category_scores_gemma":[0.1295627,0.001120687,0.003437594,0.001427279,0.001946802,0.003654384,0.002961713,0.006619957,0.03265335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005842312,"about_ca_system_score_gemma":0.009769361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003562373,"about_ca_topic_score_gemma":0.005383888,"domain_scores_codex":[0.9863883,0.003639281,0.002367478,0.001600129,0.00528864,0.0007161158],"domain_scores_gemma":[0.8108906,0.01775986,0.01052839,0.004289774,0.1485335,0.007997938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005591612,0.000006526209,0.00007896168,0.001123365,0.00002058519,0.00003571016,0.0000167525,0.00001789957,0.00007563041,0.00009048496,0.992406,0.006072226],"study_design_scores_gemma":[0.0003143008,0.00007053511,0.001212005,0.00353489,0.0001015931,0.0003113598,0.000100739,0.0001958233,0.0003486888,0.000874471,0.9928681,0.0000676193],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.0004465378,0.01263133,0.001385734,0.3323169,0.6390836,0.002036587,0.003668674,0.0008632746,0.007567405],"genre_scores_gemma":[0.007367145,0.01661754,0.002954591,0.5357454,0.3690126,0.006529966,0.003262893,0.001075189,0.05743478],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0631386,"threshold_uncertainty_score":0.2112197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01665100800406978,"score_gpt":0.2595473264109152,"score_spread":0.2428963184068454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}