{"id":"W4399654129","doi":"10.1016/j.omton.2024.200826","title":"Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancer","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy Oncology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Institute of Cancer Research; Institut Du Cancer de Montréal; Université de Montréal; Ovarian Cancer Canada; Fondation du cancer du sein du Québec","keywords":"Oncolytic virus; Vesicular stomatitis virus; Ovarian cancer; Ruxolitinib; Virotherapy; Medicine; Cancer research; Virology; Oncology; Virus; Cancer; Immunology; Internal medicine; Myelofibrosis; Bone marrow","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001818731,0.00017838,0.0004627551,0.0002637649,0.0001244777,0.0003958121,0.0001385127,0.0001715961,0.0008426275],"category_scores_gemma":[0.0001245464,0.00007467612,0.0002346015,0.0002069625,0.0001549157,0.0001928734,0.0001368778,0.0004408138,0.0001151137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001976733,"about_ca_system_score_gemma":0.0002167717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003965565,"about_ca_topic_score_gemma":0.001574819,"domain_scores_codex":[0.9998809,0.00003321625,0.00001136666,0.00001564558,0.00003136456,0.00002756735],"domain_scores_gemma":[0.9999406,0.00001736248,0.00001158913,0.000008653478,0.000006156933,0.00001558126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0016057,0.0005824126,0.002456859,0.0002942843,0.0001299266,0.00009700126,0.00005946284,0.001208239,0.9526799,0.0003252685,0.0004716469,0.04008924],"study_design_scores_gemma":[0.0003635816,0.01314719,0.02197424,0.00004668487,0.0002912139,0.0008633026,0.0001258943,0.003675588,0.9411306,0.0001891314,0.01817383,0.00001859505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885538,0.008973855,0.0005972109,0.0001500689,0.00007036002,0.00004265272,0.0001752226,0.00003114629,0.001405731],"genre_scores_gemma":[0.9956238,0.002795653,0.0005916614,0.00003811869,0.00001652434,0.00001684839,0.0002235567,0.000006736941,0.0006871044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008426275,"threshold_uncertainty_score":0.002818882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01142931745830149,"score_gpt":0.3174423639702004,"score_spread":0.3060130465118989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}