{"id":"W4399670224","doi":"10.1124/pharmrev.124.001017","title":"Pharmacology and Precision Medicine—Preparing for the Next Era in Clinical Medicine—Editorial","year":2024,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Honor; Privilege (computing); Engineering ethics; Medicine; Political science; Law; Computer science; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002411031,0.001374209,0.002132218,0.001908577,0.0005282555,0.003024835,0.001562282,0.003304696,0.007673742],"category_scores_gemma":[0.005909932,0.0003104675,0.0008783672,0.001207071,0.0007469513,0.003059871,0.00129104,0.005222256,0.005312959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009392662,"about_ca_system_score_gemma":0.002558634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005379615,"about_ca_topic_score_gemma":0.001594249,"domain_scores_codex":[0.9986932,0.0003240268,0.0001445951,0.0001379147,0.0005969281,0.000103299],"domain_scores_gemma":[0.9957675,0.001593945,0.0003820983,0.0001004555,0.001577122,0.0005788565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007453308,0.00002329503,0.00003384519,0.001852849,0.00004465138,0.00009360094,0.00001387386,0.00004571623,0.0002036878,0.001023641,0.922446,0.0741444],"study_design_scores_gemma":[0.00004966754,0.00004463819,0.0002324682,0.001798537,0.00006911786,0.0003907605,0.00002417073,0.00007923578,0.00009243621,0.001547527,0.9956582,0.00001321141],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"editorial","genre_scores_codex":[0.0001108232,0.4911027,0.0005038386,0.03460686,0.4707705,0.00003475286,0.00009442195,0.00008223464,0.002693872],"genre_scores_gemma":[0.001100156,0.4417187,0.0004960119,0.03733667,0.5112129,0.00003604114,0.0001396435,0.00003157671,0.007928292],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.007673742,"threshold_uncertainty_score":0.02567124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5457612831235339,"score_gpt":0.6281871811351069,"score_spread":0.08242589801157296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}