{"id":"W4399688762","doi":"10.2337/db24-282-or","title":"282-OR: Nod1 Plays a Causal Role in Western-Diet–Induced Insulin Resistance and Glucose Intolerance in Microbiota-Deficient Conditions","year":2024,"lang":"en","type":"article","venue":"Diabetes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"NOD1; Insulin resistance; Internal medicine; Endocrinology; Insulin; Biology; Impaired glucose tolerance; Type 2 diabetes; Innate immune system; Diabetes mellitus; Receptor; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001890237,0.0006233036,0.0003282974,0.0003341209,0.0002001415,0.0003336285,0.0002732982,0.0004945523,0.006602388],"category_scores_gemma":[0.0001070242,0.0001726917,0.0003698543,0.0001914742,0.0005164873,0.0003841549,0.0004007727,0.001053246,0.001073957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563768,"about_ca_system_score_gemma":0.0001381777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001570339,"about_ca_topic_score_gemma":0.0001758973,"domain_scores_codex":[0.9998001,0.00003191258,0.00001978072,0.00006825421,0.00003407586,0.00004581946],"domain_scores_gemma":[0.9997776,0.0000116702,0.00009135952,0.00002022596,0.00001393698,0.00008511113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001663539,0.0001693239,0.001280016,0.0001701794,0.0000170804,0.000457761,0.0000288247,0.00003379183,0.993489,0.000191601,0.0001574527,0.002341481],"study_design_scores_gemma":[0.0004029914,0.003288892,0.07624715,0.0001474593,0.0001921614,0.006172869,0.0005014527,0.00172957,0.8960426,0.0007668991,0.01446913,0.0000386898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910036,0.002350261,0.002947889,0.0004352625,0.000165797,0.00003859028,0.0008239682,0.0001454374,0.002089073],"genre_scores_gemma":[0.9868546,0.001373134,0.002487227,0.0003471267,0.00006204798,0.000105391,0.001052876,0.00007155792,0.007646159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006602388,"threshold_uncertainty_score":0.02208716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009141998416467597,"score_gpt":0.2618721952975225,"score_spread":0.2527301968810549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}