{"id":"W4399694609","doi":"10.1093/infdis/jiae308","title":"Dolutegravir- Versus Efavirenz-Based Treatment in Pregnancy: Impact on Red Blood Cell Folate Concentrations in Pregnant Women and Their Infants","year":2024,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; National Institutes of Health","keywords":"Tenofovir alafenamide; Efavirenz; Dolutegravir; Medicine; Pregnancy; Emtricitabine; Gestational age; Human immunodeficiency virus (HIV); Obstetrics; Gestation; Viral load; Immunology; Antiretroviral therapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00173933,0.0002369886,0.0006327849,0.0001277978,0.0001020523,0.0003748078,0.0003298007,0.0005878398,0.001370719],"category_scores_gemma":[0.003920942,0.0001927598,0.000692983,0.0001578081,0.0003292738,0.0002572371,0.0003164662,0.0007602046,0.0001014142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006688031,"about_ca_system_score_gemma":0.000759097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002014617,"about_ca_topic_score_gemma":0.002490933,"domain_scores_codex":[0.9990764,0.0006512785,0.00004959785,0.00008872156,0.00005544598,0.00007853453],"domain_scores_gemma":[0.9992394,0.0003889335,0.0001910436,0.0000375089,0.00001981446,0.0001232873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8430456,0.004143095,0.03067769,0.0007516304,0.00168619,0.0001284584,0.0002215613,0.001675454,0.003074325,0.0004117546,0.000469655,0.1137146],"study_design_scores_gemma":[0.2740362,0.5249097,0.1752009,0.0007625124,0.005229098,0.000597521,0.000480497,0.006849384,0.005831801,0.001621916,0.004431915,0.00004854074],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954449,0.00327469,0.00009837029,0.0003000026,0.00003041531,0.00008341789,0.0001642786,0.000006505076,0.00059746],"genre_scores_gemma":[0.9984018,0.000846421,0.0001941362,0.0001324463,0.00001225925,0.00009695371,0.00008271769,0.000001539702,0.0002317843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002014617,"threshold_uncertainty_score":0.009198546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01581252130693988,"score_gpt":0.303902943898986,"score_spread":0.2880904225920461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}