{"id":"W4399715786","doi":"10.1016/j.jpeds.2024.114158","title":"Oral Clonidine-Based Strategy to Reduce Opiate Use During Cooling for Neonatal Encephalopathy: An Observational Study","year":2024,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Thomas Wilson Sanitarium For Children of Baltimore City; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Wilson Foundation","keywords":"Clonidine; Observational study; Medicine; Opiate; Encephalopathy; Anesthesia; Neonatal encephalopathy; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007275818,0.0004890915,0.0009750155,0.0003087867,0.0006181694,0.0006212004,0.0005114538,0.0007648916,0.001241097],"category_scores_gemma":[0.003784443,0.0004581746,0.001509419,0.000739489,0.0006012571,0.0006707014,0.0004408896,0.001340314,0.0001848457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009756883,"about_ca_system_score_gemma":0.001763162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008042632,"about_ca_topic_score_gemma":0.0101413,"domain_scores_codex":[0.99907,0.0002672064,0.0001788921,0.0002055773,0.0001080378,0.00017029],"domain_scores_gemma":[0.997354,0.0007632544,0.001135125,0.0001893248,0.0002130498,0.0003452778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01076377,0.003253924,0.9737701,0.0003540745,0.002514645,0.0008406619,0.0005865846,0.000145496,0.0008305605,0.0001248651,0.0004319239,0.006383381],"study_design_scores_gemma":[0.002129426,0.01327382,0.9758552,0.000282099,0.002340148,0.001893882,0.001810522,0.0009505966,0.000357467,0.000183052,0.000848782,0.00007498018],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991726,0.0004335429,0.00008082113,0.00003286563,0.0000118612,0.00002394191,0.000111341,0.00000125141,0.000131789],"genre_scores_gemma":[0.9989886,0.000418123,0.0001436268,0.0001258454,0.00002093967,0.00003730894,0.0001970533,0.000002614005,0.00006591207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008042632,"threshold_uncertainty_score":0.01599163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1416566908215904,"score_gpt":0.3716933431441131,"score_spread":0.2300366523225227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}