{"id":"W4399717671","doi":"10.1016/j.talanta.2024.126442","title":"Serum metabolomics reveals the effectiveness of human placental mesenchymal stem cell therapy for Crohn's disease","year":2024,"lang":"en","type":"article","venue":"Talanta","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China Stem Cell and Translational Research","keywords":"Chemistry; Mesenchymal stem cell; Crohn's disease; Cell; Disease; Cell therapy; Metabolomics; Cell biology; Internal medicine; Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001664163,0.0002614651,0.0003355524,0.000359768,0.0000851713,0.0002503483,0.0000636964,0.0002171472,0.0005407311],"category_scores_gemma":[0.0001990724,0.00007780386,0.0001783555,0.0002578667,0.0001785343,0.0001402772,0.0001294263,0.0002865537,0.00008940524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001648814,"about_ca_system_score_gemma":0.0001948648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004514199,"about_ca_topic_score_gemma":0.000661011,"domain_scores_codex":[0.9998779,0.00002655957,0.000008170939,0.00002729687,0.00004063263,0.00001938052],"domain_scores_gemma":[0.9999213,0.00001027663,0.00002852986,0.000007622259,0.00001359294,0.00001871821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001876203,0.0000441362,0.004280476,0.00004602001,0.00002506475,0.00007193644,0.00002262076,0.00009131029,0.9855924,0.00002789479,0.00004439829,0.0078775],"study_design_scores_gemma":[0.00004513732,0.001671172,0.05078217,0.00001160902,0.0001182006,0.00036115,0.00008384246,0.00166402,0.943312,0.00008480027,0.001855032,0.00001093666],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940742,0.003232102,0.00172456,0.00007819351,0.00001927611,0.00001646311,0.0003233658,0.00003893366,0.0004928719],"genre_scores_gemma":[0.9966364,0.00106022,0.001338612,0.00006425893,0.0000066864,0.00001659461,0.000271132,0.000008483767,0.0005975619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005407311,"threshold_uncertainty_score":0.001808941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03234261485716717,"score_gpt":0.3330773906216117,"score_spread":0.3007347757644445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}