{"id":"W4399740896","doi":"10.1016/j.bbrep.2024.101752","title":"Autophagy unraveled: Navigating cell fate and disease dynamics","year":2024,"lang":"en","type":"editorial","venue":"Biochemistry and Biophysics Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Autophagy; Cell fate determination; Biology; Cell biology; Computational biology; Disease; Genetics; Transcription factor; Apoptosis; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001265175,0.0005301353,0.0005702912,0.00002953655,0.0001254262,0.0001330344,0.00006885581,0.0006593175,0.00001605794],"category_scores_gemma":[0.0001600845,0.0004704458,0.0002045586,0.0001422593,0.0002223728,0.00004710687,0.0001664602,0.0009461023,0.000005769463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001078769,"about_ca_system_score_gemma":0.0008983816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002639001,"about_ca_topic_score_gemma":2.31809e-7,"domain_scores_codex":[0.9976234,0.00001311924,0.0004886806,0.0009936059,0.0005541022,0.0003270548],"domain_scores_gemma":[0.9981442,0.00007961361,0.0003283533,0.0005967105,0.0001673133,0.0006837931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005413292,0.0007690021,0.000362951,0.02437301,0.0009630842,0.03695584,0.000215225,0.000001022805,0.1107691,0.00007517011,0.8089573,0.016017],"study_design_scores_gemma":[0.003359583,0.0006004971,0.0004060355,0.01236057,0.007311626,0.0009816013,0.0003078156,0.00266546,0.533945,0.01743333,0.4160934,0.004535081],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6474698,0.0232451,0.00002169856,0.0002702679,0.3249585,0.0005825129,0.001104424,0.0003438355,0.002003893],"genre_scores_gemma":[0.5448486,0.002327723,0.0001178987,0.0001145483,0.4355904,0.00005226086,0.005581241,0.0001479545,0.01121933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4231759,"threshold_uncertainty_score":0.9997748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003884244255847554,"score_gpt":0.2589413471256176,"score_spread":0.2550571028697701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}