{"id":"W4399750787","doi":"10.1152/ajpregu.00056.2024","title":"Valine administration in the hypothalamus alters the brain and plasma metabolome in rainbow trout","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Aquaculture Nutrition and Growth","field":"Agricultural and Biological Sciences","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Agencia Estatal de Investigación; Xunta de Galicia; Natural Sciences and Engineering Research Council of Canada; Ministerio de Ciencia e Innovación","keywords":"Valine; Metabolite; Endocrinology; Internal medicine; Leucine; Phenylalanine; Taurine; Tyrosine; Amino acid; Biology; Metabolome; Rainbow trout; Hypothalamus; Metabolism; Biochemistry; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009180635,0.0003571269,0.0003654724,0.0002213069,0.0002466574,0.0003357924,0.0001527107,0.0002863964,0.001457778],"category_scores_gemma":[0.0001761022,0.0002044262,0.0003036009,0.0001284065,0.0006294286,0.0003088892,0.0002666929,0.0009488139,0.0001539169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006186612,"about_ca_system_score_gemma":0.0005677987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003116718,"about_ca_topic_score_gemma":0.007220493,"domain_scores_codex":[0.9998963,0.00001059597,0.000007323783,0.00003631122,0.00001865078,0.00003097114],"domain_scores_gemma":[0.9998534,0.00001726902,0.00004569191,0.00001645412,0.00001709794,0.0000501395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001663137,0.00004109272,0.0005442551,0.00002497753,0.00001598283,0.00003824514,0.00003790707,0.00005217176,0.9967508,0.00003975299,0.00003686862,0.0007546972],"study_design_scores_gemma":[0.0001305926,0.003068984,0.04148727,0.0000124242,0.00007987041,0.0001195422,0.0001778857,0.001036521,0.9525949,0.0001268931,0.001141778,0.00002342927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985549,0.000323264,0.0003683073,0.0001001792,0.00002950802,0.000009053712,0.0002253759,0.00003801249,0.0003513393],"genre_scores_gemma":[0.9962075,0.0003454243,0.0007206691,0.0001148883,0.00001936137,0.00004858744,0.0003275634,0.00003496416,0.002180921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003116718,"threshold_uncertainty_score":0.006197155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02632758441431862,"score_gpt":0.2774893562073892,"score_spread":0.2511617717930706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}