{"id":"W4399767497","doi":"10.1084/jem.20231827","title":"Human CD127 negative ILC2s show immunological memory","year":2024,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of British Columbia; University Health Network; Terry Fox Research Institute","funders":"Canadian Institutes of Health Research; Sanofi Genzyme; Novo Nordisk Fonden; Knut och Alice Wallenbergs Stiftelse; European Research Council; Vetenskapsrådet; Karolinska Institutet; Sanofi","keywords":"Interleukin-7 receptor; Innate lymphoid cell; Immunology; Biology; Immune system; Immunity; T cell; IL-2 receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001576957,0.0002308463,0.0001510728,0.0003153425,0.0001606862,0.0003250489,0.0001175773,0.0002718851,0.004106521],"category_scores_gemma":[0.0002732276,0.00007654849,0.0001444078,0.0002159502,0.0001616944,0.000146065,0.0001879844,0.0002492515,0.0005659892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546816,"about_ca_system_score_gemma":0.0001306549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003616021,"about_ca_topic_score_gemma":0.0003902817,"domain_scores_codex":[0.9998622,0.00001508118,0.00001112209,0.00003271963,0.00003266277,0.00004628615],"domain_scores_gemma":[0.9998285,0.00003757825,0.00002992864,0.00003151162,0.00002965309,0.00004280948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000419287,0.00004109506,0.004422991,0.00004542558,0.000009340365,0.0004220777,0.00008499096,0.00005362885,0.9881897,0.0001964923,0.0003984284,0.005716563],"study_design_scores_gemma":[0.0001251371,0.001341162,0.1358706,0.00006888203,0.0001025209,0.0151247,0.00043214,0.002015352,0.8059765,0.0005457897,0.03835648,0.00004081596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926298,0.00184095,0.001380214,0.0001057848,0.00002389676,0.00003590707,0.0004681413,0.00006957894,0.00344583],"genre_scores_gemma":[0.9956166,0.0004255417,0.0008267788,0.00008832768,0.00001870306,0.00003849565,0.001080035,0.00001556249,0.001889931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004106521,"threshold_uncertainty_score":0.01373768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03034939408643899,"score_gpt":0.3086544617789117,"score_spread":0.2783050676924727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}