{"id":"W4399769620","doi":"10.1371/journal.ppat.1012315","title":"CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan","year":2024,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University; Hospital for Sick Children; Institute of Infection and Immunity; McGill University Health Centre","funders":"University of Crete; Bundesministerium für Bildung und Forschung; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft","keywords":"Aspergillus fumigatus; Degranulation; Effector; Immune system; Microbiology; Biology; Chemokine; Cytotoxic T cell; Natural killer T cell; Natural killer cell; Aspergillosis; Immunology; T cell; Receptor; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007722509,0.0003331774,0.0001576998,0.000104059,0.0001115971,0.0002246319,0.00006475237,0.000155752,0.001824815],"category_scores_gemma":[0.0001437632,0.00007342906,0.0001859201,0.00007681503,0.0001219827,0.0001136958,0.0002798332,0.0002031848,0.0003930226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001707904,"about_ca_system_score_gemma":0.0001187045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002852867,"about_ca_topic_score_gemma":0.000388586,"domain_scores_codex":[0.9998662,0.00003116374,0.00001554495,0.00002589119,0.00002274951,0.0000384491],"domain_scores_gemma":[0.9999657,0.000006737024,0.000007395787,0.000006445062,0.000005023189,0.000008703552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002039382,0.00001214488,0.001272284,0.00005825829,0.000006230755,0.0002677158,0.00001942679,0.00004504291,0.9948221,0.00009251552,0.00005981784,0.003140481],"study_design_scores_gemma":[0.00004581738,0.0002995309,0.03322117,0.00001911305,0.00003150881,0.002374364,0.0001042007,0.0009944236,0.9560463,0.0001576917,0.006697519,0.000008334453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945522,0.001852727,0.001128258,0.00005540591,0.00004253668,0.00002915894,0.000160818,0.00003080567,0.002148063],"genre_scores_gemma":[0.9975675,0.0004823155,0.0005540133,0.00002813167,0.000009302674,0.00001202576,0.0001722199,0.000002666298,0.001171853],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001824815,"threshold_uncertainty_score":0.006104648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01193696222160367,"score_gpt":0.2269626424821931,"score_spread":0.2150256802605895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}