{"id":"W4399784033","doi":"10.1093/neuonc/noae064.540","title":"MDB-92. EFFECT OF REDUCED-DOSE CRANIOSPINAL IRRADIATION AND REDUCED-DOSE ADJUVANT CHEMOTHERAPY ON CHILDREN AND ADOLESCENTS WITH WNT MEDULLOBLASTOMA WITHOUT RESIDUAL OR METASTATIC DISEASE: RESULTS FROM THE SJMB12 CLINICAL TRIAL","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Centre Hospitalier Universitaire Sainte-Justine; Alberta Children's Hospital","funders":"","keywords":"Medulloblastoma; Medicine; Adjuvant; Chemotherapy; Oncology; Adjuvant chemotherapy; Clinical trial; Disease; Internal medicine; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009791828,0.000643314,0.001634049,0.0002820819,0.0001984007,0.0006519358,0.0005460669,0.0006072241,0.001947654],"category_scores_gemma":[0.0006936144,0.0002181699,0.001093026,0.0003908068,0.0004208654,0.0003314397,0.0002416937,0.001927368,0.0003388625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007220213,"about_ca_system_score_gemma":0.001042294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002011572,"about_ca_topic_score_gemma":0.006031532,"domain_scores_codex":[0.9996182,0.0002165528,0.00002498437,0.00004591474,0.0000368531,0.00005743586],"domain_scores_gemma":[0.999501,0.0001010897,0.0001271645,0.00003016931,0.00002538704,0.000215261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8470185,0.009172013,0.018789,0.001335157,0.002928247,0.0001701842,0.0001510646,0.001636341,0.0109147,0.0002602556,0.003050211,0.1045743],"study_design_scores_gemma":[0.6231931,0.2888405,0.07343753,0.0002485551,0.003004399,0.0004256725,0.0001194917,0.001299953,0.003236462,0.0002804172,0.00587513,0.00003872594],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912217,0.005880314,0.000115187,0.0003277049,0.00006633545,0.0003456002,0.001046158,0.00003198858,0.0009651792],"genre_scores_gemma":[0.992537,0.003459399,0.000468912,0.0004025908,0.00008335788,0.0005811579,0.001632318,0.00001256666,0.000822703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002011572,"threshold_uncertainty_score":0.006515503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0278449845270876,"score_gpt":0.3569852122955307,"score_spread":0.3291402277684431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}