{"id":"W4399787813","doi":"10.1093/neuonc/noae064.003","title":"ATRT-03. PRIMARY DIFFUSE LEPTOMENINGEAL ATYPICAL TERATOID/RHABDOID TUMOR (ATRT) OF CHILDHOOD DEMONSTRATING UNEXPECTED IMPROVEMENT UPON CESSATION OF CONVENTIONAL THERAPY FOR PRESUMED PROGRESSION; A MOLECULARLY CHARACTERIZED CASE REPORT","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Atypical teratoid rhabdoid tumor; Medicine; Pathology; Oncology; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003247179,0.00022401,0.0003831602,0.00007992824,0.00008151172,0.00002679446,0.0001321285,0.0002081401,0.00001778777],"category_scores_gemma":[0.0001652958,0.0001993464,0.0002391174,0.000114504,0.0001046405,0.00001327867,0.00008020388,0.0001745995,5.058039e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006370599,"about_ca_system_score_gemma":0.0006674606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009844167,"about_ca_topic_score_gemma":0.000005214226,"domain_scores_codex":[0.9979857,0.0001503817,0.0008109885,0.0005650156,0.0002274072,0.0002605438],"domain_scores_gemma":[0.9988455,0.0001033149,0.0004663519,0.0002940781,0.0002070418,0.00008370504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001069584,0.0005396414,0.0004116263,0.0001767074,0.0001537361,0.0006372393,0.000169496,0.00001483078,0.9703932,0.00002311681,0.00007446732,0.02633637],"study_design_scores_gemma":[0.00453577,0.003497738,0.001289339,0.0001145987,0.00008090016,0.003747743,0.00006589987,0.002796463,0.9810434,0.0000502675,0.002540875,0.0002370244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942724,0.0008262221,0.003102988,0.0001781219,0.0004013568,0.001022404,0.00007931879,0.00004236514,0.00007485686],"genre_scores_gemma":[0.9948463,0.00007895013,0.003716117,0.0001409284,0.0002639721,0.0003663038,0.0005294292,0.00004273641,0.00001522833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02609934,"threshold_uncertainty_score":0.812911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137535861243506,"score_gpt":0.2981042778859546,"score_spread":0.2867289192735196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}