{"id":"W4399787848","doi":"10.1093/neuonc/noae064.068","title":"DIPG-15. NOVEL CNS SENSING SYNNOTCH-CAR T CELLS FOR TARGETING DIFFUSE MIDLINE GLIOMA","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; University of Toronto","funders":"","keywords":"Glioma; Medicine; Neuroscience; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006386184,0.0002967092,0.0001420426,0.0001628993,0.000067753,0.000185614,0.000200452,0.0003071319,0.0008801105],"category_scores_gemma":[0.00003634738,0.00007468709,0.0001446658,0.00009606989,0.0001094372,0.0001142318,0.0001439559,0.0003319792,0.000266279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002603033,"about_ca_system_score_gemma":0.0001743599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007129649,"about_ca_topic_score_gemma":0.0008018635,"domain_scores_codex":[0.9999429,0.000006407996,0.000003276788,0.00001470892,0.00001341236,0.00001923553],"domain_scores_gemma":[0.9999833,0.000001657037,0.000003646487,0.000002206185,0.000002575494,0.000006461547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001044044,0.00005064808,0.0002100154,0.00005767486,0.000005944533,0.00008600137,0.00001404195,0.0003414557,0.9936522,0.0003357483,0.000152193,0.004989726],"study_design_scores_gemma":[0.00008446414,0.001300663,0.001714095,0.000006195871,0.00003251071,0.0006233138,0.00001932167,0.003779229,0.9864432,0.00008621181,0.005905062,0.000005849742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826809,0.002042963,0.01038325,0.0001298816,0.00004947896,0.0001998095,0.0003682504,0.0002375992,0.003907958],"genre_scores_gemma":[0.9929816,0.0004524796,0.00423089,0.00006067936,0.000006849898,0.00005555786,0.0002434811,0.000008915465,0.00195952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008801105,"threshold_uncertainty_score":0.002944291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04177343121070988,"score_gpt":0.3488444550367787,"score_spread":0.3070710238260689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}