{"id":"W4399798796","doi":"10.5267/j.ccl.2024.4.002","title":"Synthesis and evaluation of novel thiophene-dhpms designed having anti-breast cancer potential","year":2024,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Thiophene; Breast cancer; Cancer; Combinatorial chemistry; Organic chemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015985,0.0002776709,0.0001747333,0.000191128,0.00009506943,0.0001298819,0.0002776413,0.0002041321,0.001666589],"category_scores_gemma":[0.0001253962,0.0001069837,0.0001514931,0.000174353,0.0001178612,0.0001655249,0.0001320883,0.0002537281,0.0002684519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001883122,"about_ca_system_score_gemma":0.0001701939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003358731,"about_ca_topic_score_gemma":0.0008433794,"domain_scores_codex":[0.9999619,0.00000745294,0.000003609992,0.000007935686,0.0000105059,0.000008689603],"domain_scores_gemma":[0.9999508,0.000006229887,0.00001397389,0.000005523265,0.00001003696,0.00001346746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003570231,0.0001723536,0.0002654835,0.0003992014,0.00002818133,0.0003164895,0.0000547335,0.002214403,0.977707,0.0006063154,0.000262028,0.01761668],"study_design_scores_gemma":[0.0001057198,0.004941549,0.001722379,0.00002690214,0.00005087793,0.000430502,0.00003879879,0.001520413,0.9782879,0.0001387988,0.01271897,0.00001722021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848685,0.003795416,0.004369164,0.0001457436,0.00005233895,0.000233415,0.0007927773,0.00009244979,0.00565009],"genre_scores_gemma":[0.9842295,0.003245102,0.008276983,0.00009034871,0.00001370976,0.00009135158,0.0007291735,0.00001186052,0.00331185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666589,"threshold_uncertainty_score":0.00557524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04366144040593405,"score_gpt":0.2946022723023314,"score_spread":0.2509408318963973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}