{"id":"W4399805565","doi":"10.1099/mgen.0.001257","title":"Plasmid genomic epidemiology of carbapenem-hydrolysing class D β-lactamase (CDHL)-producing Enterobacterales in Canada, 2010−2021","year":2024,"lang":"en","type":"article","venue":"Microbial Genomics","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital; Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Plasmid; Biology; Klebsiella pneumoniae; Horizontal gene transfer; Mobile genetic elements; Genome; Genetics; Transposable element; Gene; Microbiology; Virology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004491385,0.0002760399,0.0004715864,0.000106623,0.00004660303,0.00002079498,0.0003330629,0.0001927488,0.00006254658],"category_scores_gemma":[0.00007865596,0.0002693128,0.0001372317,0.00008983741,0.0001237178,0.000007967091,0.0002293848,0.0002159267,0.00001697868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005255686,"about_ca_system_score_gemma":0.001080525,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.1606382,"about_ca_topic_score_gemma":0.5128635,"domain_scores_codex":[0.997759,0.0001652536,0.0007425991,0.0007133142,0.00005913893,0.0005607207],"domain_scores_gemma":[0.9991739,0.00006106976,0.0001298609,0.0005117103,0.00003904522,0.00008444797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001214116,0.00001912899,0.0334862,0.0001079622,0.00008533499,0.00003039417,0.000110062,0.001381322,0.9622918,0.00001561519,0.001522646,0.0008281511],"study_design_scores_gemma":[0.0005813318,0.0000951287,0.05300209,0.000198918,0.00006080488,0.00009403736,0.0001228881,0.0007828964,0.9085596,0.00004804848,0.03585293,0.0006013113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954138,0.002301072,0.0001992549,0.0002796948,0.001350945,0.0002020895,0.0001448307,0.000007178151,0.0001010997],"genre_scores_gemma":[0.9967452,0.000485205,0.001382102,0.0002582579,0.0004206732,0.000003099337,0.0003200164,0.00005567288,0.0003297505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3522253,"threshold_uncertainty_score":0.9999759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199855918142465,"score_gpt":0.2281380362394926,"score_spread":0.2161394770580679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}