{"id":"W4399828253","doi":"10.32920/26052766.v1","title":"MICAL1 in Tumour Cell Motility","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Motility; Cell biology; Actin cytoskeleton; Tyrosine kinase; Cancer research; MAPK/ERK pathway; Receptor tyrosine kinase; Protein kinase B; Cell migration; Biology; PI3K/AKT/mTOR pathway; Metastasis; Kinase; Cell; Cytoskeleton; Signal transduction; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001083855,0.0002945791,0.0001707225,0.00029166,0.0003551042,0.0008469163,0.0001700247,0.00057724,0.006559022],"category_scores_gemma":[0.0001927611,0.0001242494,0.0001857992,0.0001910617,0.000246054,0.0003218389,0.000495006,0.0005409783,0.003095809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005374469,"about_ca_system_score_gemma":0.0002744688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007301303,"about_ca_topic_score_gemma":0.0008762197,"domain_scores_codex":[0.9998989,0.00001076419,0.00000298364,0.0000204449,0.00003956488,0.00002737445],"domain_scores_gemma":[0.9999473,0.000006579936,0.000009581625,0.000005467052,0.00001104566,0.00001998136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009543163,0.0001829893,0.003933532,0.0007672206,0.00005482172,0.001749992,0.000267791,0.00174791,0.798935,0.04344497,0.03248192,0.1154796],"study_design_scores_gemma":[0.0001226367,0.0005676877,0.07006511,0.0001791584,0.00006986605,0.003963449,0.0005250153,0.008389901,0.5848305,0.02148971,0.3097366,0.00006041318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7358074,0.0709241,0.008072796,0.01177818,0.002031239,0.00008835996,0.002022554,0.0007186502,0.1685566],"genre_scores_gemma":[0.8984738,0.009814598,0.001877333,0.0003118202,0.0002547459,0.00003193576,0.001157919,0.00008229475,0.08799549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006559022,"threshold_uncertainty_score":0.02194208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05790490133556206,"score_gpt":0.2976382133287426,"score_spread":0.2397333119931805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}