{"id":"W4399828264","doi":"10.32920/26052781.v1","title":"Loss of Functional PMRA as Pathoadaptaion in the Shigella Spp","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; University of Toronto","funders":"","keywords":"Biology; Shigella dysenteriae; Shigella; Shigella flexneri; Microbiology; Genetics; Pathogen; Shigella boydii; Transmission (telecommunications); Gene; Escherichia coli; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006082122,0.000245077,0.0001564763,0.000212184,0.000108701,0.000282751,0.0001317548,0.0001955393,0.0006015618],"category_scores_gemma":[0.0001627806,0.0001075682,0.000194634,0.0002327177,0.0001638373,0.0001409411,0.0002006163,0.000350385,0.0001986346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001762168,"about_ca_system_score_gemma":0.0001197396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008952087,"about_ca_topic_score_gemma":0.001130292,"domain_scores_codex":[0.9999059,0.00001028932,0.00000880873,0.00002998262,0.00002145589,0.0000235308],"domain_scores_gemma":[0.9998902,0.00001533302,0.00003640378,0.00001593379,0.00001568999,0.00002647237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001358108,0.000017375,0.004895325,0.00002088778,0.000008622841,0.00009379499,0.00003585255,0.00006098672,0.9931436,0.0000358179,0.00001960534,0.001532321],"study_design_scores_gemma":[0.0000268145,0.001237311,0.5572444,0.00002789072,0.00009839929,0.00375493,0.0006069774,0.001704276,0.4313032,0.0002169338,0.003755259,0.00002361637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991602,0.0001456134,0.0002653092,0.00002042553,0.000002762607,0.000002632303,0.000191664,0.00001126209,0.0002001155],"genre_scores_gemma":[0.998507,0.0001230311,0.0003839685,0.00002163991,0.000001670859,0.000005550829,0.0005048297,0.000007819821,0.0004444368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008952087,"threshold_uncertainty_score":0.002012432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02571566537996578,"score_gpt":0.3039901734747533,"score_spread":0.2782745080947875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}