{"id":"W4399833897","doi":"10.1016/j.immuni.2024.05.024","title":"Autoantibodies inhibit Plasmodium falciparum growth and are associated with protection from clinical malaria","year":2024,"lang":"en","type":"letter","venue":"Immunity","topic":"Malaria Research and Control","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"NHLBI Division of Intramural Research; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Deutsche Forschungsgemeinschaft; United States Agency for International Development","keywords":"Malaria; Plasmodium falciparum; Immunology; Biology; Autoantibody; Asymptomatic; Antibody; Seroprevalence; Antigen; Disease; Autoimmunity; Virology; Serology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002394437,0.0008633253,0.001310883,0.0006359645,0.002500945,0.002142439,0.0009425082,0.02857781,0.005680787],"category_scores_gemma":[0.01468794,0.0005842625,0.000725901,0.0004730124,0.001838951,0.001575097,0.0007073953,0.01518768,0.00315927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002837737,"about_ca_system_score_gemma":0.001479684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003454748,"about_ca_topic_score_gemma":0.006313829,"domain_scores_codex":[0.9975041,0.001132124,0.0002131288,0.0001841023,0.0005376274,0.0004289848],"domain_scores_gemma":[0.9937952,0.004029836,0.0004943508,0.0002056353,0.0006942595,0.0007807892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0007933509,0.000311033,0.006340859,0.0001641604,0.00008129364,0.009142108,0.0001594598,0.00009462199,0.0009883562,0.004779797,0.9504318,0.02671318],"study_design_scores_gemma":[0.001511583,0.0007387789,0.02123478,0.0003998538,0.0001926259,0.01302711,0.0003677229,0.001225358,0.001497218,0.01239573,0.9473241,0.00008519059],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.005114979,0.00448603,0.0002052318,0.9453463,0.02348467,0.00004993125,0.0001162212,0.00006128484,0.02113532],"genre_scores_gemma":[0.05678968,0.003576993,0.0004534052,0.8106878,0.09670209,0.0001217948,0.0001185739,0.00006011634,0.03148962],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02857781,"threshold_uncertainty_score":0.02058929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0442750769673915,"score_gpt":0.3063799835969726,"score_spread":0.2621049066295811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}