{"id":"W4399909161","doi":"10.1016/j.virol.2024.110150","title":"A novel virus-like particles vaccine induces broad immune protective against deltacoronavirus in piglets","year":2024,"lang":"en","type":"article","venue":"Virology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Ministry of Agriculture and Rural Affairs of the People's Republic of China; Jiangsu Agricultural Science and Technology Innovation Fund; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; China Postdoctoral Science Foundation","keywords":"Biology; Virology; Immune system; Immunity; Porcine epidemic diarrhea virus; Vaccination; Virus; Viral shedding; Coronavirus; Microbiology; Antibody; Diarrhea; Virus-like particle; Immunology; Recombinant DNA; Coronavirus disease 2019 (COVID-19); Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002264153,0.0001892513,0.0002618058,0.00004675215,0.0001936776,0.00004427341,0.0001737659,0.0001549066,0.0001616063],"category_scores_gemma":[0.00007349077,0.00007993761,0.00008529369,0.0005927447,0.00009934319,0.0001541466,0.0001770088,0.0003074265,0.0002534483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006480398,"about_ca_system_score_gemma":0.00001164426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002576937,"about_ca_topic_score_gemma":0.01246072,"domain_scores_codex":[0.9986877,0.00009094174,0.0002903181,0.0004294556,0.0001032364,0.0003983111],"domain_scores_gemma":[0.9995904,0.0002217442,0.00004925418,0.00005802408,0.00003265967,0.00004789189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007851303,0.0001508114,0.001171218,0.0000054413,0.00003727814,0.00003013877,0.0001852902,0.00001483291,0.9258997,0.0004115337,0.0000877947,0.07192738],"study_design_scores_gemma":[0.0003431038,0.0009688704,0.947149,0.00004501354,0.0000237451,0.00005145291,0.0003368347,0.0004115514,0.02458189,0.001514019,0.02422072,0.000353782],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948597,0.002369052,0.00002823449,0.001348564,0.0002608875,0.0003320288,0.00004018351,0.0001867828,0.0005745576],"genre_scores_gemma":[0.9988648,0.0001906366,0.00005624497,0.0004482452,0.0001735963,0.0001927832,0.000009094382,0.000002453446,0.00006214069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9459778,"threshold_uncertainty_score":0.6953375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02958884707954563,"score_gpt":0.2554742222052227,"score_spread":0.2258853751256771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}