{"id":"W4399909161","doi":"10.1016/j.virol.2024.110150","title":"A novel virus-like particles vaccine induces broad immune protective against deltacoronavirus in piglets","year":2024,"lang":"en","type":"article","venue":"Virology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Ministry of Agriculture and Rural Affairs of the People's Republic of China; Jiangsu Agricultural Science and Technology Innovation Fund; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; China Postdoctoral Science Foundation","keywords":"Biology; Virology; Immune system; Immunity; Porcine epidemic diarrhea virus; Vaccination; Virus; Viral shedding; Coronavirus; Microbiology; Antibody; Diarrhea; Virus-like particle; Immunology; Recombinant DNA; Coronavirus disease 2019 (COVID-19); Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003437046,0.0006121919,0.0005215493,0.0003471798,0.0002118759,0.0004192141,0.0004275055,0.0009210909,0.001055205],"category_scores_gemma":[0.0002201006,0.0002027775,0.0004048424,0.00009379516,0.0004927564,0.0003675598,0.0002671347,0.001308294,0.0002980857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000359803,"about_ca_system_score_gemma":0.0003177965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000502073,"about_ca_topic_score_gemma":0.0004651334,"domain_scores_codex":[0.9997018,0.00003836652,0.00001880529,0.00009274368,0.00004847939,0.00009977633],"domain_scores_gemma":[0.9998178,0.00004520089,0.00003586176,0.00002258755,0.00002323481,0.00005537675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007523872,0.0008721695,0.0004135401,0.00007010949,0.00001531448,0.00008801478,0.00004120008,0.000116761,0.9945678,0.0001143217,0.00008174679,0.002866717],"study_design_scores_gemma":[0.001441213,0.03292302,0.01486453,0.00006371862,0.0001975083,0.0006975582,0.0001920262,0.00238209,0.9432138,0.00029779,0.003707998,0.00001862452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979141,0.0002184247,0.001074195,0.00006642926,0.00008747223,0.00006124059,0.00007069154,0.00004465012,0.0004627795],"genre_scores_gemma":[0.9967821,0.0002250138,0.0009869158,0.00012409,0.00004187907,0.00005759327,0.0004069283,0.00001638248,0.00135907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055205,"threshold_uncertainty_score":0.003530025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02958884707954563,"score_gpt":0.2554742222052227,"score_spread":0.2258853751256771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}