{"id":"W4399914241","doi":"10.1016/j.clcc.2024.06.003","title":"Trifluridine/Tipiracil Based Chemoradiation in locally Advanced Rectal Cancer: The Phase I/II TARC Trial","year":2024,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universitätsklinikum Hamburg-Eppendorf; Servier; Servier Canada","keywords":"Medicine; Colorectal cancer; Oncology; Internal medicine; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001250888,0.0007579279,0.0009439344,0.0002154788,0.0002119789,0.0006934042,0.0005993618,0.0008527425,0.002195789],"category_scores_gemma":[0.0004786076,0.0001933038,0.0008850861,0.000247599,0.0004635707,0.0004261733,0.0002882811,0.002555415,0.0003981924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006889678,"about_ca_system_score_gemma":0.001017604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006563654,"about_ca_topic_score_gemma":0.002037829,"domain_scores_codex":[0.999731,0.0001367299,0.00001237213,0.00004438436,0.00003012169,0.00004537066],"domain_scores_gemma":[0.9997147,0.00004822341,0.00007217786,0.00002797437,0.00002186341,0.000115067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5491108,0.03505976,0.005089086,0.00407519,0.002218385,0.0005084123,0.0004021327,0.008643999,0.1178414,0.001102377,0.01023856,0.26571],"study_design_scores_gemma":[0.5147092,0.4404265,0.01079906,0.0002569234,0.001612309,0.0009025913,0.0001187907,0.004326953,0.01667827,0.0004368949,0.00966687,0.0000655662],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863621,0.006972779,0.0008370997,0.000952611,0.0001760058,0.001552012,0.0007329821,0.0001424031,0.002271898],"genre_scores_gemma":[0.9854258,0.004072414,0.002965528,0.001197671,0.0001486527,0.001746739,0.001768389,0.00005133436,0.002623486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002195789,"threshold_uncertainty_score":0.007345617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06765726298627654,"score_gpt":0.4448688463379701,"score_spread":0.3772115833516935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}