{"id":"W4399963709","doi":"10.1093/asj/sjae131","title":"Efficacy and Safety of RelabotulinumtoxinA, a New Ready-to-Use Liquid Formulation Botulinum Toxin: Results From the READY-1 Double-Blind, Randomized, Placebo-Controlled Phase 3 Trial in Glabellar Lines","year":2024,"lang":"en","type":"article","venue":"Aesthetic Surgery Journal","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Galderma","keywords":"Medicine; Placebo; Adverse effect; Clinical endpoint; Botulinum toxin; Randomized controlled trial; Double blind; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002843087,0.001415203,0.002169025,0.0004454718,0.0005014445,0.001042852,0.0009947835,0.001964347,0.004547323],"category_scores_gemma":[0.001840573,0.0005280831,0.002345537,0.0003379483,0.001210715,0.001196474,0.0003502497,0.002964318,0.0007211188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008641383,"about_ca_system_score_gemma":0.001223958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008088675,"about_ca_topic_score_gemma":0.001459752,"domain_scores_codex":[0.9989777,0.000478451,0.00009441096,0.0001690663,0.0001325536,0.0001478129],"domain_scores_gemma":[0.9981915,0.0005169627,0.0006177697,0.0001225773,0.0001397159,0.0004114668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9228736,0.02275984,0.0009294912,0.001050219,0.001009959,0.00006887327,0.0001252891,0.0002849802,0.01847468,0.00007295769,0.0007181634,0.03163202],"study_design_scores_gemma":[0.6921278,0.2995312,0.004497442,0.00005947566,0.000697789,0.00008548926,0.00003555809,0.0003075355,0.00202722,0.00008442361,0.0005251318,0.00002104193],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897063,0.005377837,0.0005900054,0.0003276495,0.0001538261,0.002212665,0.0007766355,0.00008886724,0.0007662695],"genre_scores_gemma":[0.9916047,0.002474649,0.001236335,0.000673103,0.0002595088,0.001943785,0.0008171646,0.00003683061,0.0009538878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004547323,"threshold_uncertainty_score":0.0152123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05472000304839693,"score_gpt":0.3175678694382837,"score_spread":0.2628478663898868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}