{"id":"W4399971167","doi":"10.1186/s12915-024-01942-w","title":"Vimentin-mediated buffering of internal integrin β1 pool increases survival of cells from anoikis","year":2024,"lang":"en","type":"article","venue":"BMC Biology","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Research Foundation of Korea; Korea University","keywords":"Vimentin; Anoikis; Biology; Cancer research; Integrin; Cell biology; Metastasis; Epithelial–mesenchymal transition; Intermediate filament; Intermediate Filament Protein; Cancer; Cell; Cytoskeleton; Immunology; Biochemistry; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003136466,0.0001622737,0.0002876535,0.00009972227,0.00001794564,0.000008250696,0.0003319928,0.0003171416,0.0002658801],"category_scores_gemma":[0.0001740669,0.0001326445,0.0001612094,0.0001109614,0.0003151775,0.000002343672,0.0003225777,0.0001578073,0.00003313279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001087935,"about_ca_system_score_gemma":0.000123761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008340614,"about_ca_topic_score_gemma":0.0001790965,"domain_scores_codex":[0.9986406,0.0002640531,0.000347243,0.0004053447,0.0000774931,0.0002652636],"domain_scores_gemma":[0.9992906,0.0001919126,0.0000781632,0.0002971831,0.00007490533,0.00006722068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002724771,0.0000754664,0.04453135,0.00005125099,0.0001951432,0.000008880397,0.00002304995,0.000001398225,0.9533027,0.0001375108,0.000224242,0.001176482],"study_design_scores_gemma":[0.0003908777,0.000496918,0.003477892,0.00005001212,0.00002557836,0.00001241427,0.0001116647,0.000187162,0.9895374,0.000112811,0.005457056,0.0001402447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911724,0.00460523,0.002717432,0.000014325,0.000478156,0.0001154241,0.0002895618,0.00001639771,0.0005911202],"genre_scores_gemma":[0.9981718,0.000351737,0.0003927202,0.00002471025,0.0002256544,0.0000113198,0.0005700153,0.00001922608,0.0002328264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04105346,"threshold_uncertainty_score":0.5409086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01620394396266191,"score_gpt":0.2844872675706197,"score_spread":0.2682833236079578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}