{"id":"W4399979605","doi":"10.3390/v16071008","title":"SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR","year":2024,"lang":"en","type":"article","venue":"Viruses","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Polymeric immunoglobulin receptor; Downregulation and upregulation; Receptor; Biology; Internalization; Respiratory system; Immune system; Cell biology; Immunology; Microbiology; Gene; Biochemistry; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008741618,0.0004643611,0.0002356008,0.0001000034,0.0001189395,0.0002261112,0.0001617966,0.0003286714,0.001440568],"category_scores_gemma":[0.000125592,0.00009137672,0.0002520283,0.00005667677,0.0001977776,0.0001669696,0.0002119514,0.0004472027,0.0005858127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002563181,"about_ca_system_score_gemma":0.0001303225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002671324,"about_ca_topic_score_gemma":0.0002959774,"domain_scores_codex":[0.9998606,0.00002821759,0.000006233093,0.00002820725,0.00002787278,0.00004881619],"domain_scores_gemma":[0.9999475,0.000007019842,0.00001778275,0.00000828917,0.000008297015,0.00001101352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004467543,0.00001406998,0.0002538147,0.00001373836,0.000001398814,0.00004530234,0.000004896182,0.00002904278,0.9988921,0.00003767268,0.00002533492,0.0006380148],"study_design_scores_gemma":[0.00003676301,0.0009200522,0.02730504,0.00001295999,0.0000238915,0.001347131,0.0001070558,0.002559115,0.9612919,0.0001098123,0.006278521,0.000007865893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949207,0.001308983,0.001449312,0.00009522178,0.00003400454,0.0000156863,0.00007584874,0.00006385807,0.00203642],"genre_scores_gemma":[0.9965068,0.0004201591,0.0009725211,0.00005007396,0.0000144807,0.00001380446,0.0001741045,0.000008692128,0.001839331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001440568,"threshold_uncertainty_score":0.004819155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08740284700183869,"score_gpt":0.3872143582716318,"score_spread":0.2998115112697931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}