{"id":"W4399983965","doi":"10.1101/2024.06.23.600155","title":"RNA interactome of hypervirulent <i>Klebsiella pneumoniae</i> reveals a small RNA inhibitor of capsular mucoviscosity and virulence","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Klebsiella pneumoniae; Virulence; Interactome; Microbiology; Biology; Virology; RNA; Escherichia coli; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008516439,0.0002432741,0.0002911279,0.0003270373,0.0001941002,0.0003031511,0.000139942,0.0001984073,0.001295019],"category_scores_gemma":[0.0001291644,0.0001332641,0.000317072,0.0002045461,0.0001160063,0.0001351643,0.0001983648,0.0002548555,0.0004277519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002141978,"about_ca_system_score_gemma":0.0001300434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008717605,"about_ca_topic_score_gemma":0.001064357,"domain_scores_codex":[0.9998506,0.00001290188,0.000008088248,0.00005421782,0.00004556681,0.00002856642],"domain_scores_gemma":[0.9998875,0.00001815229,0.00004551342,0.00001008559,0.00001613224,0.00002266128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008813308,0.00000503163,0.001121512,0.00003568271,0.00001234689,0.00003808046,0.000008504803,0.00008338512,0.9973605,0.00003368887,0.00005492022,0.001158202],"study_design_scores_gemma":[0.00001746723,0.0003767138,0.1504402,0.00002052337,0.0001044226,0.001222713,0.0001162973,0.009766801,0.8294805,0.0002070447,0.008217846,0.00002941378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905772,0.001706675,0.004811969,0.0000760954,0.00001101552,0.00001252457,0.001717554,0.0001702158,0.0009166833],"genre_scores_gemma":[0.9899319,0.0005102343,0.003868596,0.00009352065,0.00001011667,0.00002280766,0.003831448,0.00004577736,0.001685482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001295019,"threshold_uncertainty_score":0.004332304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009974640491786178,"score_gpt":0.2189540577684587,"score_spread":0.2089794172766725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}