{"id":"W4399996207","doi":"10.1097/fpc.0000000000000541","title":"Healthcare provider and patient perspectives on the implementation of pharmacogenetic-guided treatment in routine clinical practice","year":2024,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Health care; Pharmacogenetics; Test (biology); Clinical Practice; Family medicine; Clinical decision support system; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01087259,0.0001535305,0.0002186349,0.0004666696,0.001018749,0.002155873,0.0003365645,0.001086133,0.003147424],"category_scores_gemma":[0.03861932,0.0002527972,0.0003832965,0.0003450197,0.0009312824,0.001501432,0.001519786,0.001085218,0.0002856601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001394602,"about_ca_system_score_gemma":0.002751617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003732115,"about_ca_topic_score_gemma":0.002961028,"domain_scores_codex":[0.9752663,0.0196812,0.001126104,0.0005490531,0.002248175,0.001129174],"domain_scores_gemma":[0.9584263,0.02483397,0.01014417,0.0005012808,0.003020398,0.003073865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"qualitative","study_design_scores_codex":[0.0006075071,0.0006599498,0.6502338,0.001075282,0.000239802,0.002624659,0.2141371,0.000517765,0.003177023,0.00172303,0.006589622,0.1184144],"study_design_scores_gemma":[0.0001623179,0.002010208,0.5128393,0.0017788,0.00019776,0.005191883,0.4384339,0.001926823,0.001782055,0.001431988,0.03406703,0.0001779681],"study_design_candidate":"qualitative","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.971199,0.001428742,0.00113777,0.01815981,0.00006506468,0.00004861701,0.0001220365,0.00001599724,0.007823027],"genre_scores_gemma":[0.9968663,0.0006552828,0.0006665063,0.001541985,0.00004040599,0.0000206738,0.00003481872,0.000003897027,0.0001700118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01087259,"threshold_uncertainty_score":0.05750042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1534057037654506,"score_gpt":0.5266863950790736,"score_spread":0.373280691313623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}