{"id":"W4399998778","doi":"10.1002/ana.27007","title":"Golden Hour Intravenous Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis","year":2024,"lang":"en","type":"review","venue":"Annals of Neurology","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Modified Rankin Scale; Thrombolysis; Medicine; Intracerebral hemorrhage; Stroke (engine); Odds ratio; Golden hour (medicine); Meta-analysis; Fibrinolytic agent; Internal medicine; Emergency medicine; Tissue plasminogen activator; Ischemic stroke; Ischemia; Subarachnoid hemorrhage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009803608,0.002108878,0.01714488,0.004569657,0.0005989773,0.002744294,0.001914916,0.001959374,0.003609465],"category_scores_gemma":[0.0234862,0.001200929,0.02695123,0.005972602,0.0005707826,0.00148101,0.001100479,0.001668005,0.0002912981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001969121,"about_ca_system_score_gemma":0.002940652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005001271,"about_ca_topic_score_gemma":0.01117205,"domain_scores_codex":[0.9924441,0.003902342,0.00185337,0.0007093655,0.0008111118,0.0002796369],"domain_scores_gemma":[0.9869631,0.00912983,0.002437931,0.0004028996,0.0008738676,0.0001924414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003045065,0.00004666242,0.004065796,0.3964474,0.5816656,0.0001467003,0.00007581624,0.0005136468,0.0002164263,0.0001227431,0.000804352,0.01284986],"study_design_scores_gemma":[0.001160129,0.000278197,0.004183014,0.02660626,0.965923,0.00009180074,0.00003726202,0.000210138,0.00009292173,0.0001384999,0.001257252,0.00002153892],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005476604,0.9929541,0.0004019682,0.000186874,0.0001211266,0.0002871684,0.0003389539,0.00001933296,0.0002139067],"genre_scores_gemma":[0.1714652,0.8227179,0.002117685,0.0008016306,0.000343443,0.001468879,0.0007136837,0.00002433276,0.0003472037],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01714488,"threshold_uncertainty_score":0.05184704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.103957150488831,"score_gpt":0.4012960532362512,"score_spread":0.2973389027474203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}