{"id":"W4400005137","doi":"10.1002/adma.202405930","title":"High‐Lactate‐Metabolizing Photosynthetic Bacteria Reprogram Tumor Immune Microenvironment","year":2024,"lang":"en","type":"article","venue":"Advanced Materials","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Hebei University; Science Fund for Creative Research Groups; Natural Science Foundation of Hebei Province; National Natural Science Foundation of China","keywords":"Tumor microenvironment; Immunotherapy; Immune system; Reprogramming; Biology; Cancer research; Bacteria; Tumor cells; Cell; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000131258,0.0003141773,0.0001756049,0.0001690285,0.0001084326,0.0003251453,0.0001218817,0.0002398082,0.0007960769],"category_scores_gemma":[0.00009813056,0.0000846404,0.0001885166,0.0001179897,0.0001339753,0.0002080183,0.0002488422,0.0004272775,0.000225457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001810642,"about_ca_system_score_gemma":0.0001771688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001714711,"about_ca_topic_score_gemma":0.000349316,"domain_scores_codex":[0.9999111,0.0000161245,0.000004431079,0.00001556313,0.0000297667,0.0000229743],"domain_scores_gemma":[0.9999417,0.000009553486,0.00002193626,0.00000567777,0.000007161354,0.00001394057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003237542,0.00001243028,0.0001063679,0.0000159978,0.000001133445,0.00001161726,0.000003664505,0.00006420636,0.9987314,0.00005446214,0.00002246713,0.0009437365],"study_design_scores_gemma":[0.000003534973,0.0001095057,0.0004970497,0.000002243959,0.000003422915,0.00003337772,0.00001115744,0.0004903871,0.9978434,0.00002763716,0.0009761128,0.000002189709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851941,0.0008791169,0.0108755,0.0001920271,0.0000455601,0.00005908151,0.0004102973,0.0001623282,0.002181891],"genre_scores_gemma":[0.9875273,0.0007661648,0.009176241,0.00009366818,0.000009185415,0.00006034629,0.0003779603,0.00003843548,0.001950683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007960769,"threshold_uncertainty_score":0.002663136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005501661381210553,"score_gpt":0.2617906552322343,"score_spread":0.2562889938510237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}