{"id":"W4400020958","doi":"10.1021/jacs.4c04089","title":"Self-Replicating DNA-Based Nanoassemblies","year":2024,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; University of Alberta","keywords":"Chemistry; DNA; Computational biology; Biophysics; Nanotechnology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001548599,0.000172417,0.0001222388,0.0001487444,0.0001055226,0.0002493901,0.000204975,0.0001994944,0.001114672],"category_scores_gemma":[0.0003216462,0.0001546722,0.0001391958,0.00009569273,0.0001813472,0.0003266381,0.0001351856,0.0002921573,0.0005801227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001991862,"about_ca_system_score_gemma":0.000141422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001632158,"about_ca_topic_score_gemma":0.0003462868,"domain_scores_codex":[0.9999068,0.00001404106,0.00000704994,0.00002863016,0.0000317741,0.00001166315],"domain_scores_gemma":[0.9998493,0.00003862291,0.00004495658,0.00002507846,0.00002248407,0.00001945685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001853163,0.00001627097,0.0001776738,0.00004349416,0.000003046677,0.00003446925,0.00003375043,0.0005259633,0.9923059,0.001031716,0.00005311845,0.005756059],"study_design_scores_gemma":[0.000004377798,0.0001512931,0.0003465266,0.000002579996,0.000003489399,0.0001071628,0.000009315258,0.002585172,0.9926115,0.0001648214,0.004009338,0.000004622915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148363,0.002764407,0.07442262,0.0001901764,0.00009091107,0.0001072121,0.000181156,0.0008524035,0.006554805],"genre_scores_gemma":[0.9677968,0.000670059,0.0260292,0.0000722074,0.00001079606,0.00005030496,0.0001762962,0.00005592711,0.0051384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114672,"threshold_uncertainty_score":0.003728926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006402838820618785,"score_gpt":0.2764377218033812,"score_spread":0.2700348829827624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}