{"id":"W4400025864","doi":"10.17615/ds6y-7f02","title":"Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease","year":2024,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; National Institutes of Health; Novo Nordisk Fonden; Ministério da Saúde; Fonds de Recherche du Québec - Santé; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Financiadora de Estudos e Projetos; Fogarty International Center; National Heart, Lung, and Blood Institute; Vetenskapsrådet; Conselho Nacional de Desenvolvimento Científico e Tecnológico; ZonMw; University College London Hospitals NHS Foundation Trust; European Commission; Novo Nordisk; National Institute for Health and Care Research; UK Research and Innovation; Queen Mary University of London; American Heart Association","keywords":"Genetic architecture; Disease; Cardiology; Cardiac arrhythmia; Internal medicine; Medicine; Atrial fibrillation; Environmental health; Quantitative trait locus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005884626,0.00009347381,0.0001053898,0.00005627869,0.0000499138,0.00004441562,0.00004961846,0.00006586998,0.000002908565],"category_scores_gemma":[0.00005457904,0.00007176601,0.0001156637,0.0001010256,0.0001010721,0.000005488082,0.0000239913,0.00004330861,3.740562e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004047985,"about_ca_system_score_gemma":0.0001690742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006181486,"about_ca_topic_score_gemma":0.000001070095,"domain_scores_codex":[0.9993661,0.00004271521,0.0000997871,0.0002743749,0.0001093227,0.0001077075],"domain_scores_gemma":[0.9996006,0.0000312245,0.00002071953,0.0002474322,0.00002578011,0.00007428198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005394225,0.00009082534,0.1074013,0.001854289,0.005285398,0.00003106918,0.0008723578,0.004442901,0.2996408,0.09563309,0.02010461,0.459249],"study_design_scores_gemma":[0.001411422,0.0007969635,0.1815182,0.0001871677,0.0009077576,0.00002136585,0.0001256407,0.002371412,0.1608419,0.03014922,0.620913,0.0007560519],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4361246,0.09331896,0.4677852,0.001102972,0.0003063409,0.0007778709,0.0001414062,0.00005877413,0.0003838974],"genre_scores_gemma":[0.990647,0.00007809758,0.008517546,0.00002336239,0.0003186903,0.00008107162,0.0001002989,0.00002060709,0.0002133059],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6008083,"threshold_uncertainty_score":0.2926533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00878569195183007,"score_gpt":0.2086584463154101,"score_spread":0.1998727543635801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}