{"id":"W4400095852","doi":"10.14283/jpad.2024.125","title":"Longitudinal Trajectories of the Cognitive Function Index in the A4 Study","year":2024,"lang":"en","type":"article","venue":"The Journal of Prevention of Alzheimer s Disease","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Avid Radiopharmaceuticals; National Institutes of Health; National Institute on Aging; Foundation for Neurologic Diseases; Eli Lilly and Company; GHR Foundation; Brigham and Women's Hospital; Eisai; Alzheimer's Association","keywords":"Index (typography); Cognition; Psychology; Function (biology); Longitudinal study; Cognitive psychology; Mathematics; Statistics; Computer science; Neuroscience","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001987662,0.00009258882,0.0001825654,0.0001526637,0.00005967052,0.00001959098,0.0001725567,0.00001922057,0.0002633121],"category_scores_gemma":[0.0001471686,0.0000408354,0.0002554596,0.000447691,0.0001683025,0.0001543278,0.00004652619,0.0003107582,0.000003212078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001349501,"about_ca_system_score_gemma":0.0003005833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001857422,"about_ca_topic_score_gemma":0.00001414525,"domain_scores_codex":[0.9978036,0.0006878588,0.0004529566,0.00008275738,0.0008559718,0.0001168193],"domain_scores_gemma":[0.9990308,0.0002056502,0.0002170382,0.0001533377,0.0003342488,0.00005898167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007809867,0.004812166,0.9553707,0.0002350374,0.004083516,0.0001103096,0.004385652,0.00001883335,0.0006912404,0.000272176,0.0006215666,0.02158893],"study_design_scores_gemma":[0.001450496,0.001422849,0.9820628,0.0006128314,0.005705907,0.00002683623,0.006665227,0.00003484329,0.0006004099,0.001353043,0.00002729679,0.00003750197],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912604,0.006208732,0.0003990179,0.0008186047,0.0002070672,0.000829616,0.000009072157,0.000003400345,0.0002640764],"genre_scores_gemma":[0.9996261,0.00007149135,0.00000226978,0.00004479442,0.0001083883,0.00001197449,0.00000157711,0.000007856196,0.0001255762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02669205,"threshold_uncertainty_score":0.2883083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04344450258360998,"score_gpt":0.3628785669264832,"score_spread":0.3194340643428732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}