{"id":"W4400117338","doi":"10.1530/rep-23-0483","title":"Stem cell-conditioned medium improves methylation patterns and quality of caprine preantral follicles","year":2024,"lang":"en","type":"article","venue":"Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Ste. Anne's Hospital","funders":"","keywords":"Andrology; Follicular phase; Oocyte; Mesenchymal stem cell; Methylation; Stromal cell; Biology; H3K4me3; Theca; DNA methylation; In vivo; Follicle; In vitro; Cell biology; Chemistry; Immunology; Endocrinology; Gene expression; Biochemistry; Genetics; Cancer research; Medicine; Gene; Promoter; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001441871,0.0002681043,0.0002517841,0.0003000305,0.000160128,0.0002808312,0.0001714976,0.0002101126,0.001399388],"category_scores_gemma":[0.0001402252,0.00009499757,0.000243532,0.0001101021,0.0001940569,0.0001874634,0.0002416651,0.0003968374,0.0001862771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020884,"about_ca_system_score_gemma":0.000203902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010634,"about_ca_topic_score_gemma":0.00200042,"domain_scores_codex":[0.999893,0.00001351675,0.00001204068,0.00002481687,0.0000398319,0.00001679819],"domain_scores_gemma":[0.9998952,0.00001350447,0.00003407325,0.000009058398,0.00001663592,0.00003147984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001928609,0.00002830408,0.000453146,0.00007085915,0.000007112635,0.00005309459,0.00003600428,0.00002330262,0.9970841,0.00002729268,0.00004406947,0.001979806],"study_design_scores_gemma":[0.00001964312,0.000734336,0.01922646,0.00001908048,0.00006137617,0.0003146594,0.000086575,0.0002789709,0.9738626,0.00002562767,0.005361689,0.000008904331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940369,0.002758038,0.001192385,0.00009642127,0.00006809441,0.00003740044,0.00033303,0.00005569514,0.001422031],"genre_scores_gemma":[0.9932632,0.001018945,0.001508704,0.00007322465,0.00002440152,0.00004147484,0.0005239245,0.00002022259,0.003525891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001399388,"threshold_uncertainty_score":0.004681468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03912678209362654,"score_gpt":0.3171460246557102,"score_spread":0.2780192425620837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}