{"id":"W4400123084","doi":"10.1042/bcj20230461","title":"Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells","year":2024,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"IκB kinase; NF-κB; Gene; NFKB1; Gene expression; Kinase; Cell biology; Biology; Cancer research; Molecular biology; Signal transduction; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003669756,0.0003842576,0.0003322728,0.0002786525,0.0002243823,0.0004824922,0.0002084851,0.00020254,0.002218815],"category_scores_gemma":[0.00019468,0.0002709869,0.0004431285,0.0003815354,0.0002779273,0.0001517429,0.000273245,0.0005775264,0.002036626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002802537,"about_ca_system_score_gemma":0.0002983834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007206423,"about_ca_topic_score_gemma":0.0007130108,"domain_scores_codex":[0.9994817,0.00007839905,0.0000575166,0.0001261801,0.0001650399,0.0000911614],"domain_scores_gemma":[0.9998683,0.00002166363,0.00002733148,0.00004284937,0.00002062833,0.00001926033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008425162,0.00002939761,0.00007202459,0.000040979,0.000003152151,0.0000358178,0.00001882145,0.00002182872,0.9987827,0.00005702039,0.00003557477,0.0008184179],"study_design_scores_gemma":[0.00005827503,0.0004687262,0.006611783,0.00002486911,0.00002087786,0.0005289481,0.00006125007,0.0008305891,0.9818082,0.0001100285,0.009467822,0.0000086575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9291785,0.0176726,0.0399423,0.0004057343,0.0002895463,0.0004012801,0.003958165,0.0005167724,0.007635083],"genre_scores_gemma":[0.9654687,0.006151846,0.01298909,0.0001475893,0.00005929988,0.000368158,0.004987438,0.00006807199,0.009759795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002218815,"threshold_uncertainty_score":0.007422686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01795825482335578,"score_gpt":0.2623460704353683,"score_spread":0.2443878156120125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}