{"id":"W4400129631","doi":"10.3390/cells13131117","title":"Anti-Adenoviral Effect of Human Argonaute 2 Alone and in Combination with Artificial microRNAs","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK Cambridge Institute, University of Cambridge; Cancer Research UK; University of Cambridge; Uppsala Universitet; Austrian Science Fund; University of Alberta","keywords":"Argonaute; Biology; Gene silencing; RNA interference; microRNA; Cell biology; RNA-induced silencing complex; Small interfering RNA; RNA; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003388069,0.0006185182,0.0004351128,0.0002745041,0.0001103862,0.0004059205,0.0002760403,0.0003132492,0.001191944],"category_scores_gemma":[0.0001993967,0.0001874052,0.0004534151,0.0001426705,0.0002246759,0.0002131896,0.0002317138,0.0005375879,0.0002726426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000221616,"about_ca_system_score_gemma":0.0002715813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005188803,"about_ca_topic_score_gemma":0.000719914,"domain_scores_codex":[0.9995989,0.0001255347,0.00004597218,0.00008327964,0.00007606939,0.00007028368],"domain_scores_gemma":[0.9998467,0.00004908393,0.00002561835,0.00002030157,0.00001441812,0.00004379443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003083654,0.00009120908,0.00008805133,0.00006112146,0.00001861802,0.00003638056,0.00001200312,0.00006163956,0.9976374,0.0000834163,0.00004508645,0.00155665],"study_design_scores_gemma":[0.00002541266,0.001040197,0.0009321559,0.000003661467,0.00002906341,0.0001128677,0.000008664318,0.0007353023,0.9950914,0.00001488994,0.002001727,0.000004640644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991384,0.003713542,0.002047107,0.00007764588,0.0001891585,0.00004310655,0.0002261708,0.0001210432,0.002198167],"genre_scores_gemma":[0.9927817,0.001112134,0.002883933,0.00006549737,0.00004553224,0.00003692332,0.0004591692,0.00002564686,0.002589459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191944,"threshold_uncertainty_score":0.003987432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006026118639102933,"score_gpt":0.2397135008904833,"score_spread":0.2336873822513804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}