{"id":"W4400172841","doi":"10.1101/2024.06.29.601326","title":"PBRM1 directs PBAF to pericentromeres and protects centromere integrity","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Medical Research Council; Cancer Research UK","keywords":"Centromere; Cell biology; Biology; Genetics; Gene; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714679,0.0002949313,0.000202585,0.000299047,0.00018686,0.000356072,0.000264846,0.0003823398,0.004135022],"category_scores_gemma":[0.0002090973,0.000125431,0.0001492745,0.0001790585,0.0002949149,0.0001724577,0.0003355809,0.0005083556,0.001525217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900054,"about_ca_system_score_gemma":0.0001223479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000380613,"about_ca_topic_score_gemma":0.0004125721,"domain_scores_codex":[0.9998745,0.00001882905,0.000007746937,0.00003854344,0.0000379245,0.00002248382],"domain_scores_gemma":[0.9998617,0.00002391037,0.0000399394,0.00002964573,0.00001354614,0.00003124633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000619557,0.000006870731,0.000447292,0.00002514019,0.000003328323,0.00006518645,0.000007304306,0.00004253766,0.9977432,0.0001742569,0.0001145604,0.001308311],"study_design_scores_gemma":[0.00001238873,0.00005719761,0.0113208,0.000006411319,0.000007227059,0.000675454,0.00002323908,0.0007945059,0.9809021,0.0001364917,0.006059712,0.000004473603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824096,0.002714933,0.009044323,0.0003630768,0.0000755036,0.00001578379,0.001063903,0.0003596885,0.003953136],"genre_scores_gemma":[0.9858608,0.0004463225,0.003421047,0.0001027903,0.00002111057,0.00001300466,0.001435313,0.0001066563,0.008592878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004135022,"threshold_uncertainty_score":0.01383299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0147819344654754,"score_gpt":0.2080302716874331,"score_spread":0.1932483372219577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}