{"id":"W4400178150","doi":"10.1007/978-1-0716-3961-0_15","title":"Recombinant AAV Purification","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Espace pour la vie; McGill University","funders":"","keywords":"Recombinant DNA; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001578632,0.002905566,0.002019519,0.002844435,0.0016303,0.001722565,0.002428178,0.001303557,0.04426867],"category_scores_gemma":[0.00146512,0.001401581,0.001762495,0.001463049,0.001002426,0.0008023588,0.001361537,0.00410215,0.06096904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001241949,"about_ca_system_score_gemma":0.001909802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003474426,"about_ca_topic_score_gemma":0.005533858,"domain_scores_codex":[0.9978085,0.0002445758,0.0002035319,0.0005735899,0.0006814401,0.000488349],"domain_scores_gemma":[0.9991909,0.0001819218,0.00004705802,0.0001927806,0.0002258193,0.0001615892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000346005,0.0004966213,0.0008167545,0.001169021,0.0001244104,0.0003554735,0.0004007813,0.00060895,0.8663655,0.01399596,0.04108296,0.0742375],"study_design_scores_gemma":[0.0001736381,0.0003105966,0.002259459,0.0002024578,0.0001250169,0.001097966,0.00006821092,0.002048012,0.4206105,0.003283748,0.5697107,0.0001097696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.05643145,0.01335156,0.6927462,0.002349071,0.002441978,0.01269735,0.05472701,0.02674359,0.1385117],"genre_scores_gemma":[0.132044,0.009401197,0.3718966,0.002112511,0.0006883476,0.007591398,0.1871174,0.004112599,0.2850359],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.04426867,"threshold_uncertainty_score":0.1480935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0349957416905169,"score_gpt":0.4420500836811246,"score_spread":0.4070543419906077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}