{"id":"W4400178881","doi":"10.1016/s2666-5247(24)00127-7","title":"Implications of subclinical tuberculosis for vaccine trial design and global effect","year":2024,"lang":"en","type":"review","venue":"The Lancet Microbe","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Engineering and Physical Sciences Research Council; Medical Research Council; European Research Council; National Institutes of Health; European and Developing Countries Clinical Trials Partnership; Wellcome Trust; Economic and Social Research Council; World Health Organization; National Institute of Allergy and Infectious Diseases; University of Edinburgh; Bill and Melinda Gates Foundation","keywords":"Subclinical infection; Tuberculosis; Tuberculosis vaccines; Medicine; Virology; Immunology; Mycobacterium tuberculosis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003046809,0.0003243763,0.003366607,0.0000719551,0.00006019907,0.00001845535,0.000322084,0.0003728824,0.00002463335],"category_scores_gemma":[0.00179843,0.0001598138,0.0007913297,0.0003125077,0.0001218201,0.0000151632,0.0001972648,0.0005249897,0.00005623371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001032365,"about_ca_system_score_gemma":0.0002569128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002732526,"about_ca_topic_score_gemma":0.000005900979,"domain_scores_codex":[0.997322,0.0008349731,0.0008173196,0.0004593741,0.00009372699,0.000472654],"domain_scores_gemma":[0.9946321,0.0042369,0.0001891134,0.0007310552,0.00006937992,0.0001414683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01038729,0.00009535752,0.00005788644,0.02845541,0.001740814,0.000004331941,0.000008361773,2.427573e-7,0.00002866645,0.0007510982,0.3748924,0.5835781],"study_design_scores_gemma":[0.009529099,0.001928014,0.00006877628,0.003537257,0.006086849,0.0002550488,8.983176e-7,0.00001435298,0.000005145687,0.0007611198,0.9776685,0.0001449337],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001129667,0.9833313,0.0004910315,0.01001613,0.0002042819,0.005199654,0.0004452562,0.00004706431,0.0001523259],"genre_scores_gemma":[0.00003591232,0.9953812,0.001139067,0.0004987864,0.001751456,0.0008580755,0.0001941818,0.00003964901,0.0001016307],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6027761,"threshold_uncertainty_score":0.6517019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1639221731922872,"score_gpt":0.4835831798484245,"score_spread":0.3196610066561372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}