{"id":"W4400179445","doi":"10.1146/annurev-virology-100422-125123","title":"Diverse Antiphage Defenses Are Widespread Among Prophages and Mobile Genetic Elements","year":2024,"lang":"en","type":"review","venue":"Annual Review of Virology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Prophage; Biology; Lysogenic cycle; Genome; Temperateness; Mobile genetic elements; Genetics; Bacterial genome size; Host (biology); Bacteriophage; Evolutionary biology; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005113871,0.0007913151,0.001065096,0.002200938,0.0003052907,0.001403506,0.0006808979,0.0008655517,0.004109921],"category_scores_gemma":[0.0005791661,0.0002372364,0.0003971941,0.001897457,0.0005449922,0.001277038,0.0007037702,0.001295926,0.002892164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005086191,"about_ca_system_score_gemma":0.001211053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008653335,"about_ca_topic_score_gemma":0.001040857,"domain_scores_codex":[0.9997764,0.0000296596,0.00002128955,0.00004633677,0.0000952129,0.00003099594],"domain_scores_gemma":[0.999673,0.0001306465,0.00005567265,0.00001228814,0.00008681813,0.00004158244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005330191,0.00004045254,0.0003182941,0.0113145,0.00005551737,0.0001396447,0.00007393557,0.0002289555,0.006137646,0.003619594,0.01062977,0.9673884],"study_design_scores_gemma":[0.000005289146,0.00008722403,0.0009098618,0.001627502,0.00005056562,0.0007141087,0.00007465485,0.00004227519,0.001178326,0.00144847,0.993844,0.0000177045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001949434,0.9979905,0.0001573664,0.0001434961,0.0001547284,0.000003743825,0.00002224877,0.000012422,0.001320548],"genre_scores_gemma":[0.001157617,0.9975848,0.0002031621,0.00009693342,0.0001489997,0.000004846763,0.00005113765,0.000002625787,0.0007497928],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004109921,"threshold_uncertainty_score":0.01374906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01413613482219867,"score_gpt":0.3215100141627824,"score_spread":0.3073738793405837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}