{"id":"W4400192714","doi":"10.1136/gutjnl-2024-bsg.147","title":"P65 Two-year efficacy and safety of mirikizumab following 104 weeks of continuous treatment: interim results from the LUCENT-3 open-label extension study","year":2024,"lang":"en","type":"article","venue":"Poster presentations","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; St. Thomas Hospital","funders":"","keywords":"Interim; Extension (predicate logic); Open label; Interim analysis; Medicine; Computer science; Clinical trial; Programming language; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002243872,0.001056428,0.001584847,0.0003817719,0.0004737428,0.0008162133,0.000624074,0.00125907,0.001728557],"category_scores_gemma":[0.0007799875,0.0003427181,0.001472991,0.0002702727,0.0007224914,0.0009071645,0.0003107115,0.002148129,0.0008351174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006232965,"about_ca_system_score_gemma":0.0005326553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008381599,"about_ca_topic_score_gemma":0.001170727,"domain_scores_codex":[0.9994264,0.0001968705,0.00003499568,0.00007015798,0.00007544928,0.0001961325],"domain_scores_gemma":[0.999213,0.0001096619,0.0002569081,0.00009016492,0.00004845241,0.0002818005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7313371,0.0518649,0.01426632,0.0004667389,0.001126129,0.0003938849,0.0002391553,0.001544846,0.06786224,0.00009570953,0.002655814,0.1281472],"study_design_scores_gemma":[0.1317296,0.7389187,0.115195,0.00004028372,0.000826514,0.0003528984,0.00006107324,0.001539409,0.009178949,0.00009995642,0.001996909,0.00006068945],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968315,0.00125525,0.0003126487,0.00009135102,0.00004141935,0.0002669084,0.0004498595,0.00008534891,0.0006656855],"genre_scores_gemma":[0.9958474,0.0004294618,0.0004279834,0.0002559449,0.00009740223,0.0003646721,0.001292445,0.00001714356,0.001267655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002243872,"threshold_uncertainty_score":0.01186687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06323462172925366,"score_gpt":0.3809744914333718,"score_spread":0.3177398697041181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}