{"id":"W4400192714","doi":"10.1136/gutjnl-2024-bsg.147","title":"P65 Two-year efficacy and safety of mirikizumab following 104 weeks of continuous treatment: interim results from the LUCENT-3 open-label extension study","year":2024,"lang":"en","type":"article","venue":"Poster presentations","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; St. Thomas Hospital","funders":"","keywords":"Interim; Extension (predicate logic); Open label; Interim analysis; Medicine; Computer science; Clinical trial; Programming language; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001962181,0.0001254362,0.000288143,0.00006217745,0.00007970965,0.00006386588,0.0001274591,0.00003073429,0.00004265922],"category_scores_gemma":[0.00006291839,0.00007998158,0.00007888384,0.0001821527,0.00008137324,0.0001210844,0.0001111643,0.00007334692,0.000004364542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003723273,"about_ca_system_score_gemma":0.00006622604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004229891,"about_ca_topic_score_gemma":0.0002948947,"domain_scores_codex":[0.9988564,0.000124951,0.0004530698,0.0002783014,0.0001729034,0.0001143739],"domain_scores_gemma":[0.9988981,0.0005280921,0.00009072182,0.0003853353,0.00005777918,0.00003994388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.1457856,0.0110175,0.04814923,0.0001952579,0.01232451,0.0003612664,0.1792976,0.000007839853,0.3422555,0.000271679,0.009348084,0.250986],"study_design_scores_gemma":[0.1185003,0.006586281,0.8197428,0.001768752,0.002429315,0.00004433695,0.02438471,0.0002763194,0.02063723,0.00009204966,0.005204951,0.0003329986],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991901,0.001977365,0.00002576492,0.001893895,0.0003224813,0.00168341,0.0002782796,0.0000241515,0.00189367],"genre_scores_gemma":[0.998581,0.0001285276,0.0001811695,0.00008083343,0.00004953073,0.00002992558,0.0001292467,0.00001858787,0.0008011862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7715936,"threshold_uncertainty_score":0.6394357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06323462172925366,"score_gpt":0.3809744914333718,"score_spread":0.3177398697041181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}