{"id":"W4400192977","doi":"10.1136/gutjnl-2024-bsg.198","title":"P116 Primary efficacy and safety of mirikizumab in moderate to severe Crohn’s disease: results of the treat-through VIVID 1 study","year":2024,"lang":"en","type":"article","venue":"Poster presentations","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Crohn's disease; Medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001528241,0.000590883,0.001970672,0.0001709939,0.0002653376,0.0006844172,0.0004212931,0.0008150883,0.002765688],"category_scores_gemma":[0.0009226007,0.0002821422,0.001460094,0.0002233831,0.0004084356,0.0003738259,0.0002384658,0.001691801,0.0004863488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000347552,"about_ca_system_score_gemma":0.0004782123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005428862,"about_ca_topic_score_gemma":0.001236118,"domain_scores_codex":[0.9994542,0.0003075542,0.00003445483,0.00006078737,0.00007787601,0.00006506276],"domain_scores_gemma":[0.9993285,0.0001586692,0.0002027156,0.00004752065,0.00004980283,0.0002128128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8207862,0.01126547,0.0078463,0.001897086,0.00198523,0.0001932621,0.0001954513,0.0006643626,0.0524231,0.0001757215,0.003526696,0.09904118],"study_design_scores_gemma":[0.5403149,0.3727154,0.06687322,0.0001856185,0.002342611,0.0005481328,0.00006589475,0.0009703566,0.009529233,0.000245919,0.006160619,0.000048094],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828912,0.009740937,0.0006053831,0.0006156441,0.0001505132,0.001116243,0.001538072,0.0000803274,0.003261573],"genre_scores_gemma":[0.9919328,0.002977704,0.0007479885,0.0005985562,0.000227536,0.0004347326,0.001532639,0.00001990515,0.001528085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002765688,"threshold_uncertainty_score":0.009252131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133443430544739,"score_gpt":0.2867964726609297,"score_spread":0.2734521296064558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}